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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHL6
All Species:
26.36
Human Site:
Y531
Identified Species:
58
UniProt:
Q8WZ60
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WZ60
NP_569713.2
621
70359
Y531
A
M
R
A
L
Y
A
Y
S
P
L
E
D
S
W
Chimpanzee
Pan troglodytes
XP_001134897
621
70398
Y531
A
M
R
A
L
Y
A
Y
S
P
L
E
D
S
W
Rhesus Macaque
Macaca mulatta
XP_001106193
619
70154
Y529
A
M
R
A
L
Y
A
Y
S
P
L
E
D
S
W
Dog
Lupus familis
XP_545220
619
70391
Y529
A
M
R
A
L
Y
A
Y
S
P
L
E
D
I
W
Cat
Felis silvestris
Mouse
Mus musculus
Q6V595
619
70172
Y529
A
M
R
A
L
Y
A
Y
S
P
L
E
D
S
W
Rat
Rattus norvegicus
Q56A24
600
68346
Y505
V
S
L
N
N
L
I
Y
V
A
G
G
L
T
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509167
613
69325
Y523
A
M
K
A
L
Y
S
Y
S
P
L
E
D
V
W
Chicken
Gallus gallus
NP_001026474
316
35882
T227
E
E
A
Q
V
F
E
T
V
M
N
W
V
R
Y
Frog
Xenopus laevis
Q6NRH0
564
63190
G475
N
D
H
I
Y
V
V
G
G
F
D
G
T
A
H
Zebra Danio
Brachydanio rerio
Q5U374
564
62914
G475
N
D
H
I
Y
V
V
G
G
F
D
G
T
A
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUU5
623
68905
Y531
E
L
S
S
A
E
R
Y
N
P
L
T
N
T
W
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.8
97
N.A.
94.3
44.1
N.A.
82.2
40.2
29.7
29.4
N.A.
31.2
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
99.3
98.8
N.A.
96.7
58.9
N.A.
88.8
45.4
46.3
45.8
N.A.
49.1
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
100
6.6
N.A.
80
0
0
0
N.A.
26.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
100
13.3
N.A.
93.3
20
6.6
6.6
N.A.
60
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
55
0
10
55
10
0
46
0
0
10
0
0
0
19
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
19
0
0
0
0
0
0
0
0
19
0
55
0
0
% D
% Glu:
19
10
0
0
0
10
10
0
0
0
0
55
0
0
0
% E
% Phe:
0
0
0
0
0
10
0
0
0
19
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
19
19
0
10
28
0
0
0
% G
% His:
0
0
19
0
0
0
0
0
0
0
0
0
0
0
19
% H
% Ile:
0
0
0
19
0
0
10
0
0
0
0
0
0
10
0
% I
% Lys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
10
% K
% Leu:
0
10
10
0
55
10
0
0
0
0
64
0
10
0
0
% L
% Met:
0
55
0
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
19
0
0
10
10
0
0
0
10
0
10
0
10
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
64
0
0
0
0
0
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
46
0
0
0
10
0
0
0
0
0
0
10
0
% R
% Ser:
0
10
10
10
0
0
10
0
55
0
0
0
0
37
0
% S
% Thr:
0
0
0
0
0
0
0
10
0
0
0
10
19
19
0
% T
% Val:
10
0
0
0
10
19
19
0
19
0
0
0
10
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
64
% W
% Tyr:
0
0
0
0
19
55
0
73
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _