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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ROBO4
All Species:
10.3
Human Site:
S533
Identified Species:
32.38
UniProt:
Q8WZ75
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WZ75
NP_061928.4
1007
107457
S533
A
D
T
W
R
S
T
S
G
S
R
D
L
S
S
Chimpanzee
Pan troglodytes
XP_508841
908
97520
L458
S
E
H
G
P
W
T
L
E
Q
L
R
A
T
L
Rhesus Macaque
Macaca mulatta
XP_001106913
1300
139057
W576
K
N
S
I
T
L
T
W
E
P
N
P
Q
T
G
Dog
Lupus familis
XP_546424
1050
111614
S582
A
D
T
W
R
S
T
S
G
S
R
D
L
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8C310
1012
108481
S534
A
D
T
W
R
S
T
S
G
S
R
D
L
S
S
Rat
Rattus norvegicus
Q80W87
961
102562
C499
L
L
L
G
I
A
V
C
I
Y
R
R
R
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516844
829
87327
R380
R
L
A
P
Q
L
A
R
L
S
S
P
W
P
S
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001164069
1396
153618
S931
R
P
G
M
L
A
T
S
A
S
N
Y
P
W
L
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.9
23.7
80.6
N.A.
77.1
73.5
N.A.
42.2
N.A.
22
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
88.9
34.9
84.9
N.A.
84.4
79.4
N.A.
50.7
N.A.
36.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
6.6
100
N.A.
100
6.6
N.A.
13.3
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
26.6
100
N.A.
100
20
N.A.
20
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
38
0
13
0
0
25
13
0
13
0
0
0
13
0
13
% A
% Cys:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% C
% Asp:
0
38
0
0
0
0
0
0
0
0
0
38
0
0
0
% D
% Glu:
0
13
0
0
0
0
0
0
25
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
13
25
0
0
0
0
38
0
0
0
0
0
13
% G
% His:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
13
13
0
0
0
13
0
0
0
0
0
0
% I
% Lys:
13
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% K
% Leu:
13
25
13
0
13
25
0
13
13
0
13
0
38
0
25
% L
% Met:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
13
0
0
0
0
0
0
0
0
25
0
0
0
0
% N
% Pro:
0
13
0
13
13
0
0
0
0
13
0
25
13
13
0
% P
% Gln:
0
0
0
0
13
0
0
0
0
13
0
0
13
0
0
% Q
% Arg:
25
0
0
0
38
0
0
13
0
0
50
25
13
0
0
% R
% Ser:
13
0
13
0
0
38
0
50
0
63
13
0
0
38
50
% S
% Thr:
0
0
38
0
13
0
75
0
0
0
0
0
0
25
0
% T
% Val:
0
0
0
0
0
0
13
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
38
0
13
0
13
0
0
0
0
13
13
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
13
0
13
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _