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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DNASE2B
All Species:
34.55
Human Site:
S168
Identified Species:
63.33
UniProt:
Q8WZ79
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WZ79
NP_067056.2
361
41713
S168
T
G
R
R
N
G
Q
S
G
I
C
I
T
F
K
Chimpanzee
Pan troglodytes
XP_524754
357
41222
S164
T
G
R
R
N
G
Q
S
G
I
C
I
T
F
K
Rhesus Macaque
Macaca mulatta
XP_001106353
361
41660
S168
T
G
R
R
N
G
Q
S
G
I
C
I
T
F
K
Dog
Lupus familis
XP_537097
358
41217
T164
T
G
R
R
H
G
Q
T
G
I
C
I
T
F
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9QY48
354
40775
T161
S
G
R
R
Y
G
Q
T
G
I
C
I
T
F
G
Rat
Rattus norvegicus
Q9QZK9
356
40454
S163
S
G
R
Q
Y
A
Q
S
G
L
C
I
T
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507235
348
37739
S157
T
A
R
P
K
G
Q
S
F
L
C
V
S
F
S
Chicken
Gallus gallus
NP_001032927
363
40865
T165
S
G
E
S
Y
G
Q
T
A
I
C
I
T
F
S
Frog
Xenopus laevis
NP_001086671
349
38720
C158
H
N
G
Q
S
F
L
C
V
T
Y
P
Y
K
Q
Zebra Danio
Brachydanio rerio
XP_691451
335
38242
T144
T
G
K
Y
Y
G
Q
T
L
L
C
I
T
F
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650672
366
41322
K171
L
K
G
E
D
L
E
K
V
G
Q
I
L
V
Y
Honey Bee
Apis mellifera
XP_396933
375
42824
S180
S
G
T
L
Y
G
Q
S
F
L
C
I
S
L
G
Nematode Worm
Caenorhab. elegans
P34508
378
43329
S165
C
I
S
Y
N
T
V
S
L
A
T
I
A
Q
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
97.5
83.3
N.A.
65.6
65
N.A.
38.2
53.9
39.6
44.8
N.A.
32.7
31.2
31.4
N.A.
Protein Similarity:
100
98.6
98.3
90.5
N.A.
77.8
77.8
N.A.
55.1
66.9
57.6
60.3
N.A.
51.9
51.7
50
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
73.3
60
N.A.
46.6
53.3
0
53.3
N.A.
6.6
40
20
N.A.
P-Site Similarity:
100
100
100
100
N.A.
86.6
80
N.A.
66.6
66.6
20
73.3
N.A.
20
60
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
8
0
0
8
8
0
0
8
0
0
% A
% Cys:
8
0
0
0
0
0
0
8
0
0
77
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
8
8
0
0
8
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
8
0
0
16
0
0
0
0
62
0
% F
% Gly:
0
70
16
0
0
70
0
0
47
8
0
0
0
0
16
% G
% His:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
0
47
0
85
0
0
0
% I
% Lys:
0
8
8
0
8
0
0
8
0
0
0
0
0
8
39
% K
% Leu:
8
0
0
8
0
8
8
0
16
31
0
0
8
16
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
31
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% P
% Gln:
0
0
0
16
0
0
77
0
0
0
8
0
0
8
16
% Q
% Arg:
0
0
54
39
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
31
0
8
8
8
0
0
54
0
0
0
0
16
0
16
% S
% Thr:
47
0
8
0
0
8
0
31
0
8
8
0
62
0
0
% T
% Val:
0
0
0
0
0
0
8
0
16
0
0
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
16
39
0
0
0
0
0
8
0
8
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _