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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDB2
All Species:
13.64
Human Site:
S318
Identified Species:
33.33
UniProt:
Q92466
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92466
NP_000098.1
427
47864
S318
E
I
R
V
Y
S
A
S
Q
W
D
C
P
L
G
Chimpanzee
Pan troglodytes
XP_001167874
422
47209
S313
E
I
R
V
Y
S
A
S
Q
W
D
C
P
L
G
Rhesus Macaque
Macaca mulatta
XP_001109935
427
47827
S318
E
I
R
I
Y
S
A
S
Q
W
D
C
P
L
G
Dog
Lupus familis
XP_540746
413
46089
Q308
A
Q
L
L
T
T
D
Q
K
S
E
L
R
V
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q99J79
432
48357
S318
E
I
R
V
Y
S
A
S
Q
W
D
S
P
L
N
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZJL7
507
57293
C338
N
E
I
R
V
Y
S
C
S
D
W
T
K
P
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q2YDS1
496
55845
S320
N
E
I
R
V
Y
S
S
Y
D
W
S
K
P
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797961
510
57218
F407
L
D
D
K
I
S
I
F
E
T
E
S
A
K
E
Poplar Tree
Populus trichocarpa
XP_002299813
557
62379
I386
R
L
R
I
W
D
S
I
F
G
N
L
D
S
P
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q6NQ88
557
62811
I388
R
I
R
I
W
D
S
I
F
G
N
L
D
L
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
98.5
83.8
N.A.
77.3
N.A.
N.A.
N.A.
47.9
N.A.
42.7
N.A.
N.A.
N.A.
N.A.
22.9
Protein Similarity:
100
98.8
99
88.9
N.A.
86.3
N.A.
N.A.
N.A.
60.3
N.A.
60
N.A.
N.A.
N.A.
N.A.
41.3
P-Site Identity:
100
100
93.3
0
N.A.
86.6
N.A.
N.A.
N.A.
0
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
33.3
N.A.
86.6
N.A.
N.A.
N.A.
6.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
22.9
N.A.
N.A.
22.4
N.A.
N.A.
Protein Similarity:
40.2
N.A.
N.A.
40
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
40
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
40
0
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
30
0
0
0
% C
% Asp:
0
10
10
0
0
20
10
0
0
20
40
0
20
0
10
% D
% Glu:
40
20
0
0
0
0
0
0
10
0
20
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
10
20
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
20
0
0
0
0
30
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
50
20
30
10
0
10
20
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
0
0
0
0
10
0
0
0
20
10
0
% K
% Leu:
10
10
10
10
0
0
0
0
0
0
0
30
0
50
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
20
0
0
0
0
0
0
0
0
0
20
0
0
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
40
20
20
% P
% Gln:
0
10
0
0
0
0
0
10
40
0
0
0
0
0
10
% Q
% Arg:
20
0
60
20
0
0
0
0
0
0
0
0
10
0
0
% R
% Ser:
0
0
0
0
0
50
40
50
10
10
0
30
0
10
0
% S
% Thr:
0
0
0
0
10
10
0
0
0
10
0
10
0
0
0
% T
% Val:
0
0
0
30
20
0
0
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
20
0
0
0
0
40
20
0
0
0
0
% W
% Tyr:
0
0
0
0
40
20
0
0
10
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _