KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDB2
All Species:
17.88
Human Site:
S419
Identified Species:
43.7
UniProt:
Q92466
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92466
NP_000098.1
427
47864
S419
G
Y
H
I
L
I
W
S
Q
E
E
A
R
T
R
Chimpanzee
Pan troglodytes
XP_001167874
422
47209
S414
G
Y
H
I
L
I
W
S
Q
E
E
A
R
T
R
Rhesus Macaque
Macaca mulatta
XP_001109935
427
47827
S419
G
Y
H
I
L
I
W
S
Q
E
E
A
R
T
R
Dog
Lupus familis
XP_540746
413
46089
T406
E
F
N
P
M
G
D
T
L
A
S
V
M
G
E
Cat
Felis silvestris
Mouse
Mus musculus
Q99J79
432
48357
S419
G
Y
H
I
L
I
W
S
Q
E
E
D
G
S
Q
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZJL7
507
57293
S440
G
F
N
I
L
I
W
S
R
E
E
M
V
M
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q2YDS1
496
55845
N419
G
F
N
I
L
I
W
N
R
E
D
T
L
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797961
510
57218
G503
L
V
G
G
N
S
S
G
K
L
H
V
I
M
A
Poplar Tree
Populus trichocarpa
XP_002299813
557
62379
R489
S
R
S
L
F
I
W
R
P
K
E
K
S
E
P
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q6NQ88
557
62811
R491
S
R
S
L
F
I
W
R
P
Q
D
N
T
E
M
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
98.5
83.8
N.A.
77.3
N.A.
N.A.
N.A.
47.9
N.A.
42.7
N.A.
N.A.
N.A.
N.A.
22.9
Protein Similarity:
100
98.8
99
88.9
N.A.
86.3
N.A.
N.A.
N.A.
60.3
N.A.
60
N.A.
N.A.
N.A.
N.A.
41.3
P-Site Identity:
100
100
100
0
N.A.
73.3
N.A.
N.A.
N.A.
53.3
N.A.
40
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
26.6
N.A.
86.6
N.A.
N.A.
N.A.
80
N.A.
80
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
22.9
N.A.
N.A.
22.4
N.A.
N.A.
Protein Similarity:
40.2
N.A.
N.A.
40
N.A.
N.A.
P-Site Identity:
20
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
10
0
30
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
0
0
20
10
0
0
0
% D
% Glu:
10
0
0
0
0
0
0
0
0
60
60
0
0
20
10
% E
% Phe:
0
30
0
0
20
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
60
0
10
10
0
10
0
10
0
0
0
0
10
10
0
% G
% His:
0
0
40
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
60
0
80
0
0
0
0
0
0
10
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
10
10
0
10
0
0
10
% K
% Leu:
10
0
0
20
60
0
0
0
10
10
0
0
10
0
0
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
10
10
20
10
% M
% Asn:
0
0
30
0
10
0
0
10
0
0
0
10
0
0
0
% N
% Pro:
0
0
0
10
0
0
0
0
20
0
0
0
0
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
40
10
0
0
0
0
10
% Q
% Arg:
0
20
0
0
0
0
0
20
20
0
0
0
30
0
30
% R
% Ser:
20
0
20
0
0
10
10
50
0
0
10
0
10
20
10
% S
% Thr:
0
0
0
0
0
0
0
10
0
0
0
10
10
30
0
% T
% Val:
0
10
0
0
0
0
0
0
0
0
0
20
10
0
0
% V
% Trp:
0
0
0
0
0
0
80
0
0
0
0
0
0
0
0
% W
% Tyr:
0
40
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _