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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDB2
All Species:
18.48
Human Site:
Y356
Identified Species:
45.19
UniProt:
Q92466
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92466
NP_000098.1
427
47864
Y356
N
L
I
V
V
G
R
Y
P
D
P
N
F
K
S
Chimpanzee
Pan troglodytes
XP_001167874
422
47209
Y351
N
L
I
V
V
G
R
Y
P
D
P
N
F
K
S
Rhesus Macaque
Macaca mulatta
XP_001109935
427
47827
Y356
N
L
I
V
V
G
R
Y
P
D
P
N
F
K
S
Dog
Lupus familis
XP_540746
413
46089
T343
H
L
T
P
I
K
A
T
W
H
P
R
Y
N
L
Cat
Felis silvestris
Mouse
Mus musculus
Q99J79
432
48357
Y356
N
L
I
V
V
G
R
Y
P
D
P
N
L
K
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZJL7
507
57293
Y377
D
L
I
V
V
G
R
Y
P
D
P
K
F
P
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q2YDS1
496
55845
A356
P
M
Y
D
L
I
V
A
G
R
Y
P
D
D
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797961
510
57218
R440
G
R
W
L
T
V
F
R
A
A
W
H
P
R
R
Poplar Tree
Populus trichocarpa
XP_002299813
557
62379
I426
P
T
E
S
L
A
V
I
G
R
Y
I
S
E
N
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q6NQ88
557
62811
I428
T
S
E
S
L
I
V
I
G
R
Y
I
S
E
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
98.5
83.8
N.A.
77.3
N.A.
N.A.
N.A.
47.9
N.A.
42.7
N.A.
N.A.
N.A.
N.A.
22.9
Protein Similarity:
100
98.8
99
88.9
N.A.
86.3
N.A.
N.A.
N.A.
60.3
N.A.
60
N.A.
N.A.
N.A.
N.A.
41.3
P-Site Identity:
100
100
100
13.3
N.A.
93.3
N.A.
N.A.
N.A.
73.3
N.A.
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
33.3
N.A.
93.3
N.A.
N.A.
N.A.
80
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
22.9
N.A.
N.A.
22.4
N.A.
N.A.
Protein Similarity:
40.2
N.A.
N.A.
40
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
10
10
10
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
10
0
0
0
0
0
50
0
0
10
10
0
% D
% Glu:
0
0
20
0
0
0
0
0
0
0
0
0
0
20
0
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
0
0
40
0
0
% F
% Gly:
10
0
0
0
0
50
0
0
30
0
0
0
0
0
10
% G
% His:
10
0
0
0
0
0
0
0
0
10
0
10
0
0
0
% H
% Ile:
0
0
50
0
10
20
0
20
0
0
0
20
0
0
0
% I
% Lys:
0
0
0
0
0
10
0
0
0
0
0
10
0
40
0
% K
% Leu:
0
60
0
10
30
0
0
0
0
0
0
0
10
0
10
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
40
0
0
0
0
0
0
0
0
0
0
40
0
10
20
% N
% Pro:
20
0
0
10
0
0
0
0
50
0
60
10
10
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
0
10
0
0
0
0
50
10
0
30
0
10
0
10
10
% R
% Ser:
0
10
0
20
0
0
0
0
0
0
0
0
20
0
40
% S
% Thr:
10
10
10
0
10
0
0
10
0
0
0
0
0
0
0
% T
% Val:
0
0
0
50
50
10
30
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
10
0
0
0
0
0
10
0
10
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
50
0
0
30
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _