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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AQP3
All Species:
28.18
Human Site:
S275
Identified Species:
56.36
UniProt:
Q92482
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92482
NP_004916.1
292
31544
S275
H
L
E
Q
P
P
P
S
N
E
E
E
N
V
K
Chimpanzee
Pan troglodytes
XP_520531
292
31527
S275
H
L
E
Q
P
P
P
S
N
E
E
E
N
V
K
Rhesus Macaque
Macaca mulatta
XP_001099318
292
31508
S275
H
L
E
Q
P
P
P
S
T
E
Q
E
N
V
K
Dog
Lupus familis
XP_854596
292
31459
S275
H
L
E
Q
P
P
S
S
T
E
Q
E
N
V
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8R2N1
292
31549
S275
H
L
E
Q
P
P
P
S
T
E
E
E
N
V
K
Rat
Rattus norvegicus
P47862
292
31365
S275
H
L
E
Q
P
P
P
S
T
E
A
E
N
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512694
292
31482
S275
H
M
E
A
P
P
P
S
T
E
Q
E
N
V
K
Chicken
Gallus gallus
XP_424500
292
31404
A275
H
D
E
P
S
P
P
A
S
E
Q
E
T
V
K
Frog
Xenopus laevis
NP_001081876
292
31681
S275
H
I
E
P
A
P
Q
S
T
Q
Q
E
N
I
K
Zebra Danio
Brachydanio rerio
NP_001159593
299
32342
D275
H
V
K
G
E
E
R
D
K
R
E
A
V
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9ATN4
282
29541
R275
S
F
L
K
S
T
S
R
M
N
S
A
A
S
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P43549
646
70489
N598
T
G
C
E
S
P
V
N
Y
P
D
N
G
Y
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.2
95.2
N.A.
95.5
94.5
N.A.
92.4
80.8
78
64.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
98.9
97.5
N.A.
98.6
97.2
N.A.
96.5
90.4
90
78.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
86.6
80
N.A.
93.3
86.6
N.A.
73.3
53.3
46.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
86.6
N.A.
93.3
86.6
N.A.
86.6
73.3
73.3
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
27
N.A.
N.A.
20.4
N.A.
Protein Similarity:
N.A.
44.1
N.A.
N.A.
30.6
N.A.
P-Site Identity:
N.A.
0
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
6.6
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
9
0
0
9
0
0
9
17
9
0
9
% A
% Cys:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
0
0
0
9
0
0
9
0
0
0
0
% D
% Glu:
0
0
75
9
9
9
0
0
0
67
34
75
0
9
0
% E
% Phe:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
0
9
0
0
0
0
0
0
0
0
9
0
0
% G
% His:
84
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
0
0
0
0
0
0
0
0
0
9
9
% I
% Lys:
0
0
9
9
0
0
0
0
9
0
0
0
0
0
75
% K
% Leu:
0
50
9
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
9
0
0
0
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
9
17
9
0
9
67
0
0
% N
% Pro:
0
0
0
17
59
84
59
0
0
9
0
0
0
0
0
% P
% Gln:
0
0
0
50
0
0
9
0
0
9
42
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
9
9
0
9
0
0
0
0
9
% R
% Ser:
9
0
0
0
25
0
17
67
9
0
9
0
0
9
0
% S
% Thr:
9
0
0
0
0
9
0
0
50
0
0
0
9
0
0
% T
% Val:
0
9
0
0
0
0
9
0
0
0
0
0
9
67
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
9
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _