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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CFHR4
All Species:
0
Human Site:
T222
Identified Species:
0
UniProt:
Q92496
Number Species:
3
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92496
NP_006675.2
331
37299
T222
P
P
I
S
N
G
D
T
T
S
F
L
L
K
V
Chimpanzee
Pan troglodytes
Q95LB0
345
38249
K229
P
T
L
Y
Y
K
D
K
A
T
F
G
C
H
D
Rhesus Macaque
Macaca mulatta
XP_001089361
568
64145
P222
D
V
H
L
V
P
D
P
K
K
D
E
Y
K
V
Dog
Lupus familis
XP_857682
629
71277
I520
P
P
I
D
N
G
D
I
T
S
F
P
L
S
A
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.6
37.5
31.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
39.7
46.6
39.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
20
20
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
33.3
20
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
25
0
0
0
0
0
25
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
25
0
0
% C
% Asp:
25
0
0
25
0
0
100
0
0
0
25
0
0
0
25
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
25
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
75
0
0
0
0
% F
% Gly:
0
0
0
0
0
50
0
0
0
0
0
25
0
0
0
% G
% His:
0
0
25
0
0
0
0
0
0
0
0
0
0
25
0
% H
% Ile:
0
0
50
0
0
0
0
25
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
25
0
25
25
25
0
0
0
50
0
% K
% Leu:
0
0
25
25
0
0
0
0
0
0
0
25
50
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
50
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
75
50
0
0
0
25
0
25
0
0
0
25
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
25
0
0
0
0
0
50
0
0
0
25
0
% S
% Thr:
0
25
0
0
0
0
0
25
50
25
0
0
0
0
0
% T
% Val:
0
25
0
0
25
0
0
0
0
0
0
0
0
0
50
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
25
25
0
0
0
0
0
0
0
25
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _