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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX1
All Species:
30.91
Human Site:
S377
Identified Species:
48.57
UniProt:
Q92499
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92499
NP_004930.1
740
82432
S377
D
E
A
D
G
L
L
S
Q
G
Y
S
D
F
I
Chimpanzee
Pan troglodytes
XP_515309
740
82400
S377
D
E
A
D
G
L
L
S
Q
G
Y
S
D
F
I
Rhesus Macaque
Macaca mulatta
XP_001090643
740
82473
T377
D
E
A
D
G
L
L
T
Q
G
Y
S
D
F
I
Dog
Lupus familis
XP_848865
740
82396
S377
D
E
A
D
G
L
L
S
Q
G
Y
S
D
F
I
Cat
Felis silvestris
Mouse
Mus musculus
Q91VR5
740
82482
S377
D
E
A
D
G
L
L
S
Q
G
Y
S
D
F
I
Rat
Rattus norvegicus
Q641Y8
740
82479
S377
D
E
A
D
G
L
L
S
Q
G
Y
S
D
F
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90WU3
740
82466
L377
D
E
A
D
G
L
L
L
Q
G
Y
S
D
F
I
Frog
Xenopus laevis
A2VD92
740
82328
S377
D
E
A
D
G
L
L
S
Q
G
Y
S
D
F
I
Zebra Danio
Brachydanio rerio
XP_684782
740
82395
S377
D
E
C
D
G
L
L
S
A
G
N
T
D
F
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VNV3
727
80851
K377
D
E
A
D
A
L
L
K
Q
G
Y
T
E
L
I
Honey Bee
Apis mellifera
XP_392325
733
81819
K379
D
E
A
D
G
L
L
K
Q
G
Y
T
E
L
I
Nematode Worm
Caenorhab. elegans
P27639
402
45389
K67
I
V
P
C
T
T
G
K
D
V
I
A
Q
A
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84W89
633
67608
L298
L
V
A
T
P
G
R
L
N
D
L
L
E
R
A
Baker's Yeast
Sacchar. cerevisiae
P24783
546
60981
H211
T
E
C
S
K
F
G
H
S
S
R
I
R
N
T
Red Bread Mold
Neurospora crassa
Q7S5R1
614
67729
G279
Q
T
H
A
A
L
S
G
L
A
S
L
V
G
L
Conservation
Percent
Protein Identity:
100
99.8
99.5
97.6
N.A.
97.5
97.6
N.A.
N.A.
93.2
89.7
84.8
N.A.
59.7
62.9
22.4
N.A.
Protein Similarity:
100
100
100
99.1
N.A.
99.4
99.5
N.A.
N.A.
97
96
93.7
N.A.
76
78.7
36.2
N.A.
P-Site Identity:
100
100
93.3
100
N.A.
100
100
N.A.
N.A.
93.3
100
73.3
N.A.
66.6
73.3
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
93.3
100
80
N.A.
80
86.6
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.1
23.9
23.6
Protein Similarity:
N.A.
N.A.
N.A.
37.1
38.9
40.4
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
6.6
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
74
7
14
0
0
0
7
7
0
7
0
7
7
% A
% Cys:
0
0
14
7
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
74
0
0
74
0
0
0
0
7
7
0
0
60
0
0
% D
% Glu:
0
80
0
0
0
0
0
0
0
0
0
0
20
0
0
% E
% Phe:
0
0
0
0
0
7
0
0
0
0
0
0
0
60
0
% F
% Gly:
0
0
0
0
67
7
14
7
0
74
0
0
0
7
0
% G
% His:
0
0
7
0
0
0
0
7
0
0
0
0
0
0
0
% H
% Ile:
7
0
0
0
0
0
0
0
0
0
7
7
0
0
74
% I
% Lys:
0
0
0
0
7
0
0
20
0
0
0
0
0
0
0
% K
% Leu:
7
0
0
0
0
80
74
14
7
0
7
14
0
14
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
7
0
7
0
0
7
0
% N
% Pro:
0
0
7
0
7
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
7
0
0
0
0
0
0
0
67
0
0
0
7
0
7
% Q
% Arg:
0
0
0
0
0
0
7
0
0
0
7
0
7
7
0
% R
% Ser:
0
0
0
7
0
0
7
47
7
7
7
54
0
0
0
% S
% Thr:
7
7
0
7
7
7
0
7
0
0
0
20
0
0
7
% T
% Val:
0
14
0
0
0
0
0
0
0
7
0
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
67
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _