KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX1
All Species:
43.94
Human Site:
T440
Identified Species:
69.05
UniProt:
Q92499
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92499
NP_004930.1
740
82432
T440
G
E
D
S
V
P
D
T
V
H
H
V
V
V
P
Chimpanzee
Pan troglodytes
XP_515309
740
82400
T440
G
E
D
S
V
P
D
T
V
H
H
V
V
V
P
Rhesus Macaque
Macaca mulatta
XP_001090643
740
82473
T440
G
E
D
S
V
P
D
T
V
H
H
V
V
V
P
Dog
Lupus familis
XP_848865
740
82396
T440
G
E
D
S
V
P
D
T
V
H
H
V
V
V
P
Cat
Felis silvestris
Mouse
Mus musculus
Q91VR5
740
82482
T440
G
E
D
S
V
P
D
T
V
H
H
V
V
V
P
Rat
Rattus norvegicus
Q641Y8
740
82479
T440
G
E
D
S
V
P
D
T
V
H
H
V
V
V
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90WU3
740
82466
T440
G
E
D
S
V
P
E
T
V
H
H
V
V
V
I
Frog
Xenopus laevis
A2VD92
740
82328
T440
G
E
D
S
V
P
E
T
V
H
H
V
V
V
P
Zebra Danio
Brachydanio rerio
XP_684782
740
82395
T440
G
E
D
S
V
P
E
T
V
H
H
V
V
V
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VNV3
727
80851
T440
G
E
D
A
V
P
E
T
V
H
H
V
V
C
L
Honey Bee
Apis mellifera
XP_392325
733
81819
T442
G
E
D
A
V
P
E
T
V
H
H
V
V
V
I
Nematode Worm
Caenorhab. elegans
P27639
402
45389
P130
Y
L
N
V
N
I
L
P
C
I
G
G
T
S
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84W89
633
67608
Q361
A
T
F
P
R
E
I
Q
R
L
A
A
D
F
L
Baker's Yeast
Sacchar. cerevisiae
P24783
546
60981
D274
D
E
A
D
R
M
L
D
M
G
F
E
P
Q
I
Red Bread Mold
Neurospora crassa
Q7S5R1
614
67729
A342
S
F
A
V
L
D
E
A
D
R
M
L
D
R
G
Conservation
Percent
Protein Identity:
100
99.8
99.5
97.6
N.A.
97.5
97.6
N.A.
N.A.
93.2
89.7
84.8
N.A.
59.7
62.9
22.4
N.A.
Protein Similarity:
100
100
100
99.1
N.A.
99.4
99.5
N.A.
N.A.
97
96
93.7
N.A.
76
78.7
36.2
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
86.6
93.3
86.6
N.A.
73.3
80
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
93.3
100
93.3
N.A.
86.6
93.3
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.1
23.9
23.6
Protein Similarity:
N.A.
N.A.
N.A.
37.1
38.9
40.4
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
0
13.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
14
14
0
0
0
7
0
0
7
7
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
7
0
0
0
0
7
0
% C
% Asp:
7
0
74
7
0
7
40
7
7
0
0
0
14
0
0
% D
% Glu:
0
80
0
0
0
7
40
0
0
0
0
7
0
0
0
% E
% Phe:
0
7
7
0
0
0
0
0
0
0
7
0
0
7
0
% F
% Gly:
74
0
0
0
0
0
0
0
0
7
7
7
0
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
74
74
0
0
0
0
% H
% Ile:
0
0
0
0
0
7
7
0
0
7
0
0
0
0
20
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
7
0
0
7
0
14
0
0
7
0
7
0
0
14
% L
% Met:
0
0
0
0
0
7
0
0
7
0
7
0
0
0
0
% M
% Asn:
0
0
7
0
7
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
7
0
74
0
7
0
0
0
0
7
0
47
% P
% Gln:
0
0
0
0
0
0
0
7
0
0
0
0
0
7
0
% Q
% Arg:
0
0
0
0
14
0
0
0
7
7
0
0
0
7
0
% R
% Ser:
7
0
0
60
0
0
0
0
0
0
0
0
0
7
0
% S
% Thr:
0
7
0
0
0
0
0
74
0
0
0
0
7
0
7
% T
% Val:
0
0
0
14
74
0
0
0
74
0
0
74
74
67
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _