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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX1
All Species:
22.42
Human Site:
T452
Identified Species:
35.24
UniProt:
Q92499
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92499
NP_004930.1
740
82432
T452
V
V
P
V
N
P
K
T
D
R
L
W
E
R
L
Chimpanzee
Pan troglodytes
XP_515309
740
82400
T452
V
V
P
V
N
P
K
T
D
R
L
W
E
R
L
Rhesus Macaque
Macaca mulatta
XP_001090643
740
82473
T452
V
V
P
V
N
P
K
T
D
R
L
W
E
R
L
Dog
Lupus familis
XP_848865
740
82396
A452
V
V
P
V
N
P
K
A
D
R
L
W
E
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q91VR5
740
82482
T452
V
V
P
V
N
P
K
T
D
K
L
W
E
R
L
Rat
Rattus norvegicus
Q641Y8
740
82479
T452
V
V
P
V
N
P
K
T
D
R
L
W
E
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90WU3
740
82466
T452
V
V
I
V
N
P
K
T
D
K
L
W
E
R
L
Frog
Xenopus laevis
A2VD92
740
82328
K452
V
V
P
V
N
P
K
K
D
K
Q
W
E
K
L
Zebra Danio
Brachydanio rerio
XP_684782
740
82395
N452
V
V
T
V
N
P
K
N
D
K
L
W
E
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VNV3
727
80851
M452
V
C
L
V
D
P
Q
M
D
T
T
W
Q
S
L
Honey Bee
Apis mellifera
XP_392325
733
81819
K454
V
V
I
V
D
P
Q
K
D
K
S
W
H
N
L
Nematode Worm
Caenorhab. elegans
P27639
402
45389
R142
T
S
V
R
D
D
Q
R
K
L
E
A
G
I
H
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84W89
633
67608
F373
D
F
L
A
N
Y
I
F
L
A
V
G
R
V
G
Baker's Yeast
Sacchar. cerevisiae
P24783
546
60981
D286
P
Q
I
R
K
I
V
D
Q
I
R
P
D
R
Q
Red Bread Mold
Neurospora crassa
Q7S5R1
614
67729
I354
D
R
G
F
S
E
D
I
K
L
I
L
S
G
C
Conservation
Percent
Protein Identity:
100
99.8
99.5
97.6
N.A.
97.5
97.6
N.A.
N.A.
93.2
89.7
84.8
N.A.
59.7
62.9
22.4
N.A.
Protein Similarity:
100
100
100
99.1
N.A.
99.4
99.5
N.A.
N.A.
97
96
93.7
N.A.
76
78.7
36.2
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
93.3
100
N.A.
N.A.
86.6
73.3
80
N.A.
40
46.6
0
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
N.A.
93.3
86.6
86.6
N.A.
60
66.6
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.1
23.9
23.6
Protein Similarity:
N.A.
N.A.
N.A.
37.1
38.9
40.4
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
13.3
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
0
0
7
0
7
0
7
0
0
0
% A
% Cys:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
7
% C
% Asp:
14
0
0
0
20
7
7
7
74
0
0
0
7
0
0
% D
% Glu:
0
0
0
0
0
7
0
0
0
0
7
0
60
0
0
% E
% Phe:
0
7
0
7
0
0
0
7
0
0
0
0
0
0
0
% F
% Gly:
0
0
7
0
0
0
0
0
0
0
0
7
7
7
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
7
% H
% Ile:
0
0
20
0
0
7
7
7
0
7
7
0
0
7
0
% I
% Lys:
0
0
0
0
7
0
60
14
14
34
0
0
0
7
0
% K
% Leu:
0
0
14
0
0
0
0
0
7
14
54
7
0
0
74
% L
% Met:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
67
0
0
7
0
0
0
0
0
7
0
% N
% Pro:
7
0
47
0
0
74
0
0
0
0
0
7
0
0
0
% P
% Gln:
0
7
0
0
0
0
20
0
7
0
7
0
7
0
7
% Q
% Arg:
0
7
0
14
0
0
0
7
0
34
7
0
7
60
0
% R
% Ser:
0
7
0
0
7
0
0
0
0
0
7
0
7
7
0
% S
% Thr:
7
0
7
0
0
0
0
40
0
7
7
0
0
0
0
% T
% Val:
74
67
7
74
0
0
7
0
0
0
7
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
74
0
0
0
% W
% Tyr:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _