Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDX1 All Species: 22.42
Human Site: Y265 Identified Species: 35.24
UniProt: Q92499 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92499 NP_004930.1 740 82432 Y265 L S K A P D G Y I V K S Q H S
Chimpanzee Pan troglodytes XP_515309 740 82400 Y265 L S K A P D G Y I V K S Q H S
Rhesus Macaque Macaca mulatta XP_001090643 740 82473 Y265 L S K A P D G Y I V K S Q H S
Dog Lupus familis XP_848865 740 82396 Y265 L A K A S D S Y V V K S Q H T
Cat Felis silvestris
Mouse Mus musculus Q91VR5 740 82482 Y265 L S K A P D N Y I V K S Q H T
Rat Rattus norvegicus Q641Y8 740 82479 Y265 L S K A P D S Y V V K S Q H T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90WU3 740 82466 N265 L C K A P D G N V V K S Q H T
Frog Xenopus laevis A2VD92 740 82328 H265 L S K A P D G H V V K S Q N T
Zebra Danio Brachydanio rerio XP_684782 740 82395 H265 L N Q A P E G H V V K S S Q T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VNV3 727 80851 S265 C Q A G P E H S K A N P I T G
Honey Bee Apis mellifera XP_392325 733 81819 R267 S A P K E A I R E N S I N S N
Nematode Worm Caenorhab. elegans P27639 402 45389
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q84W89 633 67608 L193 Q R H A I P I L L E G R D L M
Baker's Yeast Sacchar. cerevisiae P24783 546 60981 H106 N E M T I S G H D I P K P I T
Red Bread Mold Neurospora crassa Q7S5R1 614 67729 S173 I V I K D P S S S N L R P I M
Conservation
Percent
Protein Identity: 100 99.8 99.5 97.6 N.A. 97.5 97.6 N.A. N.A. 93.2 89.7 84.8 N.A. 59.7 62.9 22.4 N.A.
Protein Similarity: 100 100 100 99.1 N.A. 99.4 99.5 N.A. N.A. 97 96 93.7 N.A. 76 78.7 36.2 N.A.
P-Site Identity: 100 100 100 66.6 N.A. 86.6 80 N.A. N.A. 73.3 73.3 46.6 N.A. 6.6 0 0 N.A.
P-Site Similarity: 100 100 100 86.6 N.A. 93.3 93.3 N.A. N.A. 86.6 100 86.6 N.A. 13.3 13.3 0 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 22.1 23.9 23.6
Protein Similarity: N.A. N.A. N.A. 37.1 38.9 40.4
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 0
P-Site Similarity: N.A. N.A. N.A. 13.3 26.6 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 14 7 67 0 7 0 0 0 7 0 0 0 0 0 % A
% Cys: 7 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 7 54 0 0 7 0 0 0 7 0 0 % D
% Glu: 0 7 0 0 7 14 0 0 7 7 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 7 0 0 47 0 0 0 7 0 0 0 7 % G
% His: 0 0 7 0 0 0 7 20 0 0 0 0 0 47 0 % H
% Ile: 7 0 7 0 14 0 14 0 27 7 0 7 7 14 0 % I
% Lys: 0 0 54 14 0 0 0 0 7 0 60 7 0 0 0 % K
% Leu: 60 0 0 0 0 0 0 7 7 0 7 0 0 7 0 % L
% Met: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 14 % M
% Asn: 7 7 0 0 0 0 7 7 0 14 7 0 7 7 7 % N
% Pro: 0 0 7 0 60 14 0 0 0 0 7 7 14 0 0 % P
% Gln: 7 7 7 0 0 0 0 0 0 0 0 0 54 7 0 % Q
% Arg: 0 7 0 0 0 0 0 7 0 0 0 14 0 0 0 % R
% Ser: 7 40 0 0 7 7 20 14 7 0 7 60 7 7 20 % S
% Thr: 0 0 0 7 0 0 0 0 0 0 0 0 0 7 47 % T
% Val: 0 7 0 0 0 0 0 0 34 60 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 40 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _