Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDX1 All Species: 36.67
Human Site: Y628 Identified Species: 57.62
UniProt: Q92499 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92499 NP_004930.1 740 82432 Y628 T E K E K V W Y H V C S S R G
Chimpanzee Pan troglodytes XP_515309 740 82400 Y628 T E K E K V W Y H V C S S R G
Rhesus Macaque Macaca mulatta XP_001090643 740 82473 Y628 T E K E K V W Y H V C S S R G
Dog Lupus familis XP_848865 740 82396 Y628 T E K E K V W Y H V C S S R G
Cat Felis silvestris
Mouse Mus musculus Q91VR5 740 82482 Y628 T E K E K V W Y H V C S N R G
Rat Rattus norvegicus Q641Y8 740 82479 Y628 T E K E K V W Y H V C S N R G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90WU3 740 82466 Y628 K E K E K V W Y H V C S S R G
Frog Xenopus laevis A2VD92 740 82328 Y628 S E K E K V W Y H V C S S R G
Zebra Danio Brachydanio rerio XP_684782 740 82395 Y628 M E K E K V W Y H V C A S R G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VNV3 727 80851 V619 V A T V P E K V W Y H G E W C
Honey Bee Apis mellifera XP_392325 733 81819 G625 P E K V W Y H G E W C S S R G
Nematode Worm Caenorhab. elegans P27639 402 45389 T294 K M T E N Q F T V S C L H G D
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q84W89 633 67608 G525 A T A F F N D G N T S L A R P
Baker's Yeast Sacchar. cerevisiae P24783 546 60981 P438 Y V I N Y D M P G N I E D Y V
Red Bread Mold Neurospora crassa Q7S5R1 614 67729 A506 G T T T V L V A T D V A A R G
Conservation
Percent
Protein Identity: 100 99.8 99.5 97.6 N.A. 97.5 97.6 N.A. N.A. 93.2 89.7 84.8 N.A. 59.7 62.9 22.4 N.A.
Protein Similarity: 100 100 100 99.1 N.A. 99.4 99.5 N.A. N.A. 97 96 93.7 N.A. 76 78.7 36.2 N.A.
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. N.A. 93.3 93.3 86.6 N.A. 0 46.6 13.3 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 93.3 100 93.3 N.A. 0 46.6 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 22.1 23.9 23.6
Protein Similarity: N.A. N.A. N.A. 37.1 38.9 40.4
P-Site Identity: N.A. N.A. N.A. 6.6 0 13.3
P-Site Similarity: N.A. N.A. N.A. 20 0 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 7 0 0 0 0 7 0 0 0 14 14 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 74 0 0 0 7 % C
% Asp: 0 0 0 0 0 7 7 0 0 7 0 0 7 0 7 % D
% Glu: 0 67 0 67 0 7 0 0 7 0 0 7 7 0 0 % E
% Phe: 0 0 0 7 7 0 7 0 0 0 0 0 0 0 0 % F
% Gly: 7 0 0 0 0 0 0 14 7 0 0 7 0 7 74 % G
% His: 0 0 0 0 0 0 7 0 60 0 7 0 7 0 0 % H
% Ile: 0 0 7 0 0 0 0 0 0 0 7 0 0 0 0 % I
% Lys: 14 0 67 0 60 0 7 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 7 0 0 0 0 0 14 0 0 0 % L
% Met: 7 7 0 0 0 0 7 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 7 7 7 0 0 7 7 0 0 14 0 0 % N
% Pro: 7 0 0 0 7 0 0 7 0 0 0 0 0 0 7 % P
% Gln: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 80 0 % R
% Ser: 7 0 0 0 0 0 0 0 0 7 7 60 54 0 0 % S
% Thr: 40 14 20 7 0 0 0 7 7 7 0 0 0 0 0 % T
% Val: 7 7 0 14 7 60 7 7 7 60 7 0 0 0 7 % V
% Trp: 0 0 0 0 7 0 60 0 7 7 0 0 0 7 0 % W
% Tyr: 7 0 0 0 7 7 0 60 0 7 0 0 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _