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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDX1 All Species: 39.7
Human Site: Y639 Identified Species: 62.38
UniProt: Q92499 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92499 NP_004930.1 740 82432 Y639 S S R G K G C Y N T R L K E D
Chimpanzee Pan troglodytes XP_515309 740 82400 Y639 S S R G K G C Y N T R L K E D
Rhesus Macaque Macaca mulatta XP_001090643 740 82473 Y639 S S R G K G C Y N T R L K E D
Dog Lupus familis XP_848865 740 82396 Y639 S S R G K G C Y N T R L K E D
Cat Felis silvestris
Mouse Mus musculus Q91VR5 740 82482 Y639 S N R G K G C Y N T R L K E D
Rat Rattus norvegicus Q641Y8 740 82479 Y639 S N R G K G C Y N T R L K E D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90WU3 740 82466 Y639 S S R G K G C Y N T R L K E E
Frog Xenopus laevis A2VD92 740 82328 Y639 S S R G K G C Y N T R L K E D
Zebra Danio Brachydanio rerio XP_684782 740 82395 Y639 A S R G K G C Y N T R L K E N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VNV3 727 80851 G630 G E W C K S R G R S C N N T N
Honey Bee Apis mellifera XP_392325 733 81819 Y636 S S R G R N C Y N T N L T D K
Nematode Worm Caenorhab. elegans P27639 402 45389 A305 L H G D M D Q A E R D T I M R
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q84W89 633 67608 L536 L A R P L A E L M Q E A N Q E
Baker's Yeast Sacchar. cerevisiae P24783 546 60981 G449 E D Y V H R I G R T G R A G A
Red Bread Mold Neurospora crassa Q7S5R1 614 67729 P517 A A R G L D I P E V K L V I N
Conservation
Percent
Protein Identity: 100 99.8 99.5 97.6 N.A. 97.5 97.6 N.A. N.A. 93.2 89.7 84.8 N.A. 59.7 62.9 22.4 N.A.
Protein Similarity: 100 100 100 99.1 N.A. 99.4 99.5 N.A. N.A. 97 96 93.7 N.A. 76 78.7 36.2 N.A.
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. N.A. 93.3 100 86.6 N.A. 6.6 60 0 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 100 100 100 N.A. 20 73.3 0 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 22.1 23.9 23.6
Protein Similarity: N.A. N.A. N.A. 37.1 38.9 40.4
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 20
P-Site Similarity: N.A. N.A. N.A. 26.6 6.6 46.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 14 0 0 0 7 0 7 0 0 0 7 7 0 7 % A
% Cys: 0 0 0 7 0 0 67 0 0 0 7 0 0 0 0 % C
% Asp: 0 7 0 7 0 14 0 0 0 0 7 0 0 7 47 % D
% Glu: 7 7 0 0 0 0 7 0 14 0 7 0 0 60 14 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 7 0 7 74 0 60 0 14 0 0 7 0 0 7 0 % G
% His: 0 7 0 0 7 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 14 0 0 0 0 0 7 7 0 % I
% Lys: 0 0 0 0 67 0 0 0 0 0 7 0 60 0 7 % K
% Leu: 14 0 0 0 14 0 0 7 0 0 0 74 0 0 0 % L
% Met: 0 0 0 0 7 0 0 0 7 0 0 0 0 7 0 % M
% Asn: 0 14 0 0 0 7 0 0 67 0 7 7 14 0 20 % N
% Pro: 0 0 0 7 0 0 0 7 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 7 0 0 7 0 0 0 7 0 % Q
% Arg: 0 0 80 0 7 7 7 0 14 7 60 7 0 0 7 % R
% Ser: 60 54 0 0 0 7 0 0 0 7 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 74 0 7 7 7 0 % T
% Val: 0 0 0 7 0 0 0 0 0 7 0 0 7 0 0 % V
% Trp: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 7 0 0 0 0 67 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _