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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX1
All Species:
39.39
Human Site:
Y653
Identified Species:
61.9
UniProt:
Q92499
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92499
NP_004930.1
740
82432
Y653
D
G
G
C
T
I
W
Y
N
E
M
Q
L
L
S
Chimpanzee
Pan troglodytes
XP_515309
740
82400
Y653
D
G
G
C
T
I
W
Y
N
E
M
Q
L
L
S
Rhesus Macaque
Macaca mulatta
XP_001090643
740
82473
Y653
D
G
G
C
T
I
W
Y
N
E
M
Q
L
L
S
Dog
Lupus familis
XP_848865
740
82396
Y653
D
G
G
C
T
I
W
Y
N
E
M
Q
L
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q91VR5
740
82482
Y653
D
G
G
C
T
I
W
Y
N
E
M
Q
L
L
S
Rat
Rattus norvegicus
Q641Y8
740
82479
Y653
D
G
G
C
T
I
W
Y
N
E
M
Q
L
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90WU3
740
82466
Y653
E
G
G
C
T
I
W
Y
N
E
M
Q
L
L
G
Frog
Xenopus laevis
A2VD92
740
82328
Y653
D
G
G
C
T
I
W
Y
N
E
M
Q
L
L
S
Zebra Danio
Brachydanio rerio
XP_684782
740
82395
Y653
N
G
G
C
T
I
W
Y
N
E
K
E
L
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VNV3
727
80851
C644
N
L
T
E
V
R
G
C
C
I
W
Y
N
E
P
Honey Bee
Apis mellifera
XP_392325
733
81819
Y650
K
G
G
C
C
I
W
Y
N
E
P
N
Y
L
A
Nematode Worm
Caenorhab. elegans
P27639
402
45389
S319
R
E
F
R
S
G
S
S
R
V
L
I
T
T
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84W89
633
67608
R550
E
V
P
E
W
L
T
R
Y
A
S
R
S
S
F
Baker's Yeast
Sacchar. cerevisiae
P24783
546
60981
F463
A
T
G
T
A
I
S
F
F
T
E
Q
N
K
G
Red Bread Mold
Neurospora crassa
Q7S5R1
614
67729
I531
N
V
T
F
P
L
T
I
E
D
Y
V
H
R
I
Conservation
Percent
Protein Identity:
100
99.8
99.5
97.6
N.A.
97.5
97.6
N.A.
N.A.
93.2
89.7
84.8
N.A.
59.7
62.9
22.4
N.A.
Protein Similarity:
100
100
100
99.1
N.A.
99.4
99.5
N.A.
N.A.
97
96
93.7
N.A.
76
78.7
36.2
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
86.6
100
80
N.A.
0
60
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
93.3
100
93.3
N.A.
6.6
66.6
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.1
23.9
23.6
Protein Similarity:
N.A.
N.A.
N.A.
37.1
38.9
40.4
P-Site Identity:
N.A.
N.A.
N.A.
0
20
0
P-Site Similarity:
N.A.
N.A.
N.A.
20
26.6
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
7
0
0
0
0
7
0
0
0
0
7
% A
% Cys:
0
0
0
67
7
0
0
7
7
0
0
0
0
0
0
% C
% Asp:
47
0
0
0
0
0
0
0
0
7
0
0
0
0
7
% D
% Glu:
14
7
0
14
0
0
0
0
7
67
7
7
0
7
0
% E
% Phe:
0
0
7
7
0
0
0
7
7
0
0
0
0
0
7
% F
% Gly:
0
67
74
0
0
7
7
0
0
0
0
0
0
0
14
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% H
% Ile:
0
0
0
0
0
74
0
7
0
7
0
7
0
0
7
% I
% Lys:
7
0
0
0
0
0
0
0
0
0
7
0
0
7
0
% K
% Leu:
0
7
0
0
0
14
0
0
0
0
7
0
60
67
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
54
0
0
0
0
% M
% Asn:
20
0
0
0
0
0
0
0
67
0
0
7
14
0
0
% N
% Pro:
0
0
7
0
7
0
0
0
0
0
7
0
0
0
7
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
60
0
0
0
% Q
% Arg:
7
0
0
7
0
7
0
7
7
0
0
7
0
7
0
% R
% Ser:
0
0
0
0
7
0
14
7
0
0
7
0
7
7
54
% S
% Thr:
0
7
14
7
60
0
14
0
0
7
0
0
7
7
0
% T
% Val:
0
14
0
0
7
0
0
0
0
7
0
7
0
0
0
% V
% Trp:
0
0
0
0
7
0
67
0
0
0
7
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
67
7
0
7
7
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _