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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEC14L1 All Species: 17.88
Human Site: S194 Identified Species: 35.76
UniProt: Q92503 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92503 NP_001034662.2 715 81278 S194 T P S S E T S S S S S K K Q A
Chimpanzee Pan troglodytes XP_001155845 715 81257 S194 T P S S E T S S S S C K K Q A
Rhesus Macaque Macaca mulatta XP_001107080 715 81245 L194 T P C S D T S L S S C K K Q A
Dog Lupus familis XP_540457 715 81255 S194 A P S S E T S S S C K K Q A A
Cat Felis silvestris
Mouse Mus musculus NP_001159978 715 81197 S194 G P S E T C S S S K N Q V T S
Rat Rattus norvegicus NP_001101779 720 81849 S194 G P S S E T C S S S K N Q A A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_415614 715 81562 S194 C K L E S S T S H T R R P V S
Frog Xenopus laevis NP_001087870 715 81309 D194 Q Q Q E T K T D T S G R A M S
Zebra Danio Brachydanio rerio NP_957392 697 79632 S194 P Q L I P V S S A K P I P A C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VMD6 659 75661 E179 E E G I T H V E R W T S P S D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q03606 719 81064 S194 E T T S A T D S A I E M K E L
Sea Urchin Strong. purpuratus XP_783768 1178 131796 E671 E E D V E K E E N K E T H L P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 98.4 95 N.A. 94.6 94.5 N.A. N.A. 91.6 86.1 76.5 N.A. 42.6 N.A. 45.2 32.9
Protein Similarity: 100 99.7 99.3 98 N.A. 97.6 97.2 N.A. N.A. 96.2 93.2 87.6 N.A. 60 N.A. 64.2 45
P-Site Identity: 100 93.3 73.3 66.6 N.A. 33.3 60 N.A. N.A. 6.6 6.6 13.3 N.A. 0 N.A. 26.6 6.6
P-Site Similarity: 100 93.3 80 73.3 N.A. 53.3 66.6 N.A. N.A. 40 33.3 20 N.A. 6.6 N.A. 46.6 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 9 0 0 0 17 0 0 0 9 25 42 % A
% Cys: 9 0 9 0 0 9 9 0 0 9 17 0 0 0 9 % C
% Asp: 0 0 9 0 9 0 9 9 0 0 0 0 0 0 9 % D
% Glu: 25 17 0 25 42 0 9 17 0 0 17 0 0 9 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 17 0 9 0 0 0 0 0 0 0 9 0 0 0 0 % G
% His: 0 0 0 0 0 9 0 0 9 0 0 0 9 0 0 % H
% Ile: 0 0 0 17 0 0 0 0 0 9 0 9 0 0 0 % I
% Lys: 0 9 0 0 0 17 0 0 0 25 17 34 34 0 0 % K
% Leu: 0 0 17 0 0 0 0 9 0 0 0 0 0 9 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 9 0 9 0 % M
% Asn: 0 0 0 0 0 0 0 0 9 0 9 9 0 0 0 % N
% Pro: 9 50 0 0 9 0 0 0 0 0 9 0 25 0 9 % P
% Gln: 9 17 9 0 0 0 0 0 0 0 0 9 17 25 0 % Q
% Arg: 0 0 0 0 0 0 0 0 9 0 9 17 0 0 0 % R
% Ser: 0 0 42 50 9 9 50 67 50 42 9 9 0 9 25 % S
% Thr: 25 9 9 0 25 50 17 0 9 9 9 9 0 9 0 % T
% Val: 0 0 0 9 0 9 9 0 0 0 0 0 9 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _