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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC39A7 All Species: 6.67
Human Site: T257 Identified Species: 11.28
UniProt: Q92504 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.31
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92504 NP_001070984.1 469 50118 T257 H G H A H S H T R G S H G H G
Chimpanzee Pan troglodytes XP_518395 246 26116 R61 E E E E K E T R G V E K R R G
Rhesus Macaque Macaca mulatta XP_001115925 469 49890 T257 H G H A H S H T H G S H G H G
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q31125 476 50638 G265 H G D R H A H G D S H T H G D
Rat Rattus norvegicus Q2M1K6 361 38379 D176 F L N C K E E D P S Q A P S K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZI20 366 39255 P180 K A P L G K I P N G S G Y P P
Frog Xenopus laevis NP_001121291 466 50701 H268 E H G H G H G H S H A A K E K
Zebra Danio Brachydanio rerio Q9PUB8 352 37904 S167 K V L L S F A S G G L L G D A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3A4 449 48639 H252 L K G G H G G H G H S H G A P
Honey Bee Apis mellifera XP_395560 404 45524 S219 H L H T N K I S I T E N L S K
Nematode Worm Caenorhab. elegans Q9XTQ7 462 49322 E261 I I A F L T V E K L V R I L R
Sea Urchin Strong. purpuratus XP_787748 239 25481 D54 T E K A K V E D D G P V K K G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M647 469 50564 D250 A G S K K L K D E G D H N N L
Baker's Yeast Sacchar. cerevisiae P40544 346 37400 D161 L S G T S N D D G S I H S H S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 48.4 97.6 N.A. N.A. 85.7 30.9 N.A. N.A. 31.1 57.1 38.1 N.A. 49.6 37.5 47.5 32.2
Protein Similarity: 100 51.1 98.5 N.A. N.A. 89.9 41.7 N.A. N.A. 44.5 70.1 47.5 N.A. 63.9 54.1 61.8 38.8
P-Site Identity: 100 6.6 93.3 N.A. N.A. 26.6 0 N.A. N.A. 13.3 0 13.3 N.A. 26.6 13.3 0 20
P-Site Similarity: 100 6.6 93.3 N.A. N.A. 33.3 6.6 N.A. N.A. 13.3 6.6 20 N.A. 26.6 33.3 13.3 20
Percent
Protein Identity: N.A. N.A. N.A. 36.6 28.7 N.A.
Protein Similarity: N.A. N.A. N.A. 50.3 43.9 N.A.
P-Site Identity: N.A. N.A. N.A. 20 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 8 22 0 8 8 0 0 0 8 15 0 8 8 % A
% Cys: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 0 0 8 29 15 0 8 0 0 8 8 % D
% Glu: 15 15 8 8 0 15 15 8 8 0 15 0 0 8 0 % E
% Phe: 8 0 0 8 0 8 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 29 22 8 15 8 15 8 29 43 0 8 29 8 29 % G
% His: 29 8 22 8 29 8 22 15 8 15 8 36 8 22 0 % H
% Ile: 8 8 0 0 0 0 15 0 8 0 8 0 8 0 0 % I
% Lys: 15 8 8 8 29 15 8 0 8 0 0 8 15 8 22 % K
% Leu: 15 15 8 15 8 8 0 0 0 8 8 8 8 8 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 8 8 0 0 8 0 0 8 8 8 0 % N
% Pro: 0 0 8 0 0 0 0 8 8 0 8 0 8 8 15 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % Q
% Arg: 0 0 0 8 0 0 0 8 8 0 0 8 8 8 8 % R
% Ser: 0 8 8 0 15 15 0 15 8 22 29 0 8 15 8 % S
% Thr: 8 0 0 15 0 8 8 15 0 8 0 8 0 0 0 % T
% Val: 0 8 0 0 0 8 8 0 0 8 8 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _