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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC39A7
All Species:
7.58
Human Site:
T270
Identified Species:
12.82
UniProt:
Q92504
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92504
NP_001070984.1
469
50118
T270
H
G
R
Q
E
R
S
T
K
E
K
Q
S
S
E
Chimpanzee
Pan troglodytes
XP_518395
246
26116
K74
R
G
G
S
T
V
P
K
D
G
P
V
R
P
Q
Rhesus Macaque
Macaca mulatta
XP_001115925
469
49890
N270
H
G
R
Q
E
R
S
N
K
E
K
Q
S
S
E
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q31125
476
50638
S278
G
D
R
H
E
C
S
S
K
E
K
P
S
T
E
Rat
Rattus norvegicus
Q2M1K6
361
38379
A189
S
K
D
P
T
A
A
A
L
N
G
G
H
C
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZI20
366
39255
K193
P
P
S
K
V
A
G
K
S
Q
R
A
E
K
N
Frog
Xenopus laevis
NP_001121291
466
50701
T281
E
K
I
V
D
D
A
T
E
K
E
E
E
K
D
Zebra Danio
Brachydanio rerio
Q9PUB8
352
37904
P180
D
A
F
L
H
L
I
P
H
A
L
E
P
H
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3A4
449
48639
P265
A
P
K
P
K
P
V
P
A
K
K
K
S
S
D
Honey Bee
Apis mellifera
XP_395560
404
45524
N232
S
K
E
N
K
D
D
N
K
L
Q
K
D
I
D
Nematode Worm
Caenorhab. elegans
Q9XTQ7
462
49322
G274
L
R
G
E
D
G
H
G
H
S
H
G
H
S
H
Sea Urchin
Strong. purpuratus
XP_787748
239
25481
R67
K
G
D
S
S
Q
V
R
R
R
K
T
G
E
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M647
469
50564
S263
N
L
D
Q
Q
S
S
S
D
A
I
V
N
S
S
Baker's Yeast
Sacchar. cerevisiae
P40544
346
37400
Q174
H
S
H
S
H
T
P
Q
Q
T
A
E
K
K
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
48.4
97.6
N.A.
N.A.
85.7
30.9
N.A.
N.A.
31.1
57.1
38.1
N.A.
49.6
37.5
47.5
32.2
Protein Similarity:
100
51.1
98.5
N.A.
N.A.
89.9
41.7
N.A.
N.A.
44.5
70.1
47.5
N.A.
63.9
54.1
61.8
38.8
P-Site Identity:
100
6.6
93.3
N.A.
N.A.
53.3
0
N.A.
N.A.
0
6.6
0
N.A.
20
6.6
6.6
13.3
P-Site Similarity:
100
13.3
93.3
N.A.
N.A.
66.6
6.6
N.A.
N.A.
20
53.3
6.6
N.A.
53.3
33.3
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.6
28.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.3
43.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
15
15
8
8
15
8
8
0
0
8
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
0
% C
% Asp:
8
8
22
0
15
15
8
0
15
0
0
0
8
0
22
% D
% Glu:
8
0
8
8
22
0
0
0
8
22
8
22
15
8
22
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
29
15
0
0
8
8
8
0
8
8
15
8
0
0
% G
% His:
22
0
8
8
15
0
8
0
15
0
8
0
15
8
8
% H
% Ile:
0
0
8
0
0
0
8
0
0
0
8
0
0
8
0
% I
% Lys:
8
22
8
8
15
0
0
15
29
15
36
15
8
22
8
% K
% Leu:
8
8
0
8
0
8
0
0
8
8
8
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
8
0
0
0
15
0
8
0
0
8
0
8
% N
% Pro:
8
15
0
15
0
8
15
15
0
0
8
8
8
8
0
% P
% Gln:
0
0
0
22
8
8
0
8
8
8
8
15
0
0
8
% Q
% Arg:
8
8
22
0
0
15
0
8
8
8
8
0
8
0
0
% R
% Ser:
15
8
8
22
8
8
29
15
8
8
0
0
29
36
15
% S
% Thr:
0
0
0
0
15
8
0
15
0
8
0
8
0
8
0
% T
% Val:
0
0
0
8
8
8
15
0
0
0
0
15
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _