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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSD17B8
All Species:
0
Human Site:
S60
Identified Species:
0
UniProt:
Q92506
Number Species:
9
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92506
NP_055049.1
261
26974
S60
R
L
L
G
G
P
G
S
K
E
G
P
P
R
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
NP_001108430
261
26939
N60
Q
L
L
G
G
P
G
N
K
E
G
P
P
R
G
Dog
Lupus familis
XP_851004
259
26677
K60
L
G
G
Q
G
S
E
K
V
A
P
G
G
A
H
Cat
Felis silvestris
Mouse
Mus musculus
P50171
259
26570
D60
L
G
S
P
G
S
E
D
G
A
P
R
G
K
H
Rat
Rattus norvegicus
Q6MGB5
259
26772
D60
L
G
N
P
G
S
E
D
R
E
P
R
G
K
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001005292
256
26946
Q60
L
P
R
E
H
R
G
Q
E
H
M
A
L
G
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_570046
249
26195
E61
S
E
R
S
A
A
L
E
V
D
V
S
S
A
Q
Honey Bee
Apis mellifera
XP_624870
246
26335
V58
S
R
H
L
A
L
N
V
E
V
L
N
E
Q
S
Nematode Worm
Caenorhab. elegans
NP_499346
296
31226
A92
V
A
D
L
K
K
S
A
A
E
A
T
A
G
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P33207
319
33530
E64
K
A
Q
A
T
A
T
E
Q
S
P
G
E
V
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96.1
88.1
N.A.
86.9
86.9
N.A.
N.A.
N.A.
N.A.
60.1
N.A.
50.5
46.3
41.8
N.A.
Protein Similarity:
100
N.A.
98
91.1
N.A.
94.2
93.4
N.A.
N.A.
N.A.
N.A.
73.5
N.A.
67.8
67.4
59.7
N.A.
P-Site Identity:
100
N.A.
86.6
6.6
N.A.
6.6
13.3
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
0
0
6.6
N.A.
P-Site Similarity:
100
N.A.
100
6.6
N.A.
13.3
26.6
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
6.6
13.3
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
20
0
10
20
20
0
10
10
20
10
10
10
20
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
20
0
10
0
0
0
0
0
% D
% Glu:
0
10
0
10
0
0
30
20
20
40
0
0
20
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
30
10
20
50
0
30
0
10
0
20
20
30
20
20
% G
% His:
0
0
10
0
10
0
0
0
0
10
0
0
0
0
30
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
0
10
10
0
10
20
0
0
0
0
20
0
% K
% Leu:
40
20
20
20
0
10
10
0
0
0
10
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
10
10
0
0
0
10
0
0
10
% N
% Pro:
0
10
0
20
0
20
0
0
0
0
40
20
20
0
0
% P
% Gln:
10
0
10
10
0
0
0
10
10
0
0
0
0
10
10
% Q
% Arg:
10
10
20
0
0
10
0
0
10
0
0
20
0
20
0
% R
% Ser:
20
0
10
10
0
30
10
10
0
10
0
10
10
0
10
% S
% Thr:
0
0
0
0
10
0
10
0
0
0
0
10
0
0
0
% T
% Val:
10
0
0
0
0
0
0
10
20
10
10
0
0
10
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _