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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PIGB All Species: 4.24
Human Site: T379 Identified Species: 7.18
UniProt: Q92521 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92521 NP_004846.4 554 65056 T379 V F C G Y S L T H L K T W K K
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_852466 348 40905 N184 V F C G Y S L N H L K T W K K
Cat Felis silvestris
Mouse Mus musculus Q9JJQ0 542 63101 A368 V F C G Y S L A H L K T W R K
Rat Rattus norvegicus NP_001101636 542 63187 A368 V F C G Y S L A H L K A W R K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514392 611 69924 N382 V F C G Y S L N S L K T W R R
Chicken Gallus gallus
Frog Xenopus laevis Q4V7R2 531 61428 S367 V F C G F S F S N L K R W K K
Zebra Danio Brachydanio rerio Q7SXZ1 536 62222 A361 I F C G L S L A K L Q A W R K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VZM5 561 64988 R368 P K L R E I A R E Y R D E R E
Honey Bee Apis mellifera XP_001122380 446 53291 Y282 P L L P M C I Y I S A R K I F
Nematode Worm Caenorhab. elegans Q23361 492 57131 L328 A V F C A R M L I N R H K S F
Sea Urchin Strong. purpuratus XP_788180 518 59872 I354 I L Y L L F N I P A S I Y F G
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001131169 550 62718 M377 S G Y C L A S M S Q S K G K N
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_568305 548 62683 A359 I F S G Y A F A Q M E V S G S
Baker's Yeast Sacchar. cerevisiae P30777 616 72547 R414 I S S F G L L R L D R D Y W K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 56.1 N.A. 77.4 78.1 N.A. 52.8 N.A. 63.5 52.8 N.A. 38.3 33 21.8 43.6
Protein Similarity: 100 N.A. N.A. 60.2 N.A. 85.7 85.3 N.A. 64.6 N.A. 77.4 72.1 N.A. 56.3 50.1 40.6 60.8
P-Site Identity: 100 N.A. N.A. 93.3 N.A. 86.6 80 N.A. 73.3 N.A. 66.6 53.3 N.A. 0 0 0 0
P-Site Similarity: 100 N.A. N.A. 93.3 N.A. 93.3 86.6 N.A. 86.6 N.A. 86.6 73.3 N.A. 20 6.6 13.3 13.3
Percent
Protein Identity: N.A. 38.9 N.A. 39.3 25.3 N.A.
Protein Similarity: N.A. 58.4 N.A. 58.3 44.4 N.A.
P-Site Identity: N.A. 6.6 N.A. 20 13.3 N.A.
P-Site Similarity: N.A. 13.3 N.A. 46.6 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 8 15 8 29 0 8 8 15 0 0 0 % A
% Cys: 0 0 50 15 0 8 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 8 0 15 0 0 0 % D
% Glu: 0 0 0 0 8 0 0 0 8 0 8 0 8 0 8 % E
% Phe: 0 58 8 8 8 8 15 0 0 0 0 0 0 8 15 % F
% Gly: 0 8 0 58 8 0 0 0 0 0 0 0 8 8 8 % G
% His: 0 0 0 0 0 0 0 0 29 0 0 8 0 0 0 % H
% Ile: 29 0 0 0 0 8 8 8 15 0 0 8 0 8 0 % I
% Lys: 0 8 0 0 0 0 0 0 8 0 43 8 15 29 50 % K
% Leu: 0 15 15 8 22 8 50 8 8 50 0 0 0 0 0 % L
% Met: 0 0 0 0 8 0 8 8 0 8 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 8 15 8 8 0 0 0 0 8 % N
% Pro: 15 0 0 8 0 0 0 0 8 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 8 8 8 0 0 0 0 % Q
% Arg: 0 0 0 8 0 8 0 15 0 0 22 15 0 36 8 % R
% Ser: 8 8 15 0 0 50 8 8 15 8 15 0 8 8 8 % S
% Thr: 0 0 0 0 0 0 0 8 0 0 0 29 0 0 0 % T
% Val: 43 8 0 0 0 0 0 0 0 0 0 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 50 8 0 % W
% Tyr: 0 0 15 0 43 0 0 8 0 8 0 0 15 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _