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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PIGB All Species: 15.76
Human Site: Y540 Identified Species: 26.67
UniProt: Q92521 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92521 NP_004846.4 554 65056 Y540 I G S H I Y V Y E R K L K G K
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_852466 348 40905 H341 P E G R T G S H I Y V Y E R K
Cat Felis silvestris
Mouse Mus musculus Q9JJQ0 542 63101 Y529 T G S H I H V Y E R R L P G R
Rat Rattus norvegicus NP_001101636 542 63187 Y529 T G S H I H V Y E R R L T S R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514392 611 69924 Y544 T G S H I Y V Y E R K K R E G
Chicken Gallus gallus
Frog Xenopus laevis Q4V7R2 531 61428 Y524 G R T G S H I Y M Y E R N S K
Zebra Danio Brachydanio rerio Q7SXZ1 536 62222 Y522 V G K N I L I Y S R R S E M K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VZM5 561 64988 E548 V H D H P P L E D L V L A N E
Honey Bee Apis mellifera XP_001122380 446 53291 H439 T S N E C T K H L K F A F I L
Nematode Worm Caenorhab. elegans Q23361 492 57131 V485 I Y T E K A V V L K N R N Y K
Sea Urchin Strong. purpuratus XP_788180 518 59872 C511 E D D N K D S C S T T N I V T
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001131169 550 62718 V543 D L Q S A V V V Y S W R D V L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_568305 548 62683 V540 D L Q S S V V V Y V V N H A F
Baker's Yeast Sacchar. cerevisiae P30777 616 72547 W590 F F N S L A H W D S R R S G D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 56.1 N.A. 77.4 78.1 N.A. 52.8 N.A. 63.5 52.8 N.A. 38.3 33 21.8 43.6
Protein Similarity: 100 N.A. N.A. 60.2 N.A. 85.7 85.3 N.A. 64.6 N.A. 77.4 72.1 N.A. 56.3 50.1 40.6 60.8
P-Site Identity: 100 N.A. N.A. 6.6 N.A. 66.6 60 N.A. 66.6 N.A. 13.3 33.3 N.A. 13.3 0 20 0
P-Site Similarity: 100 N.A. N.A. 20 N.A. 86.6 80 N.A. 73.3 N.A. 40 66.6 N.A. 40 20 33.3 6.6
Percent
Protein Identity: N.A. 38.9 N.A. 39.3 25.3 N.A.
Protein Similarity: N.A. 58.4 N.A. 58.3 44.4 N.A.
P-Site Identity: N.A. 6.6 N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. 6.6 N.A. 6.6 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 15 0 0 0 0 0 8 8 8 0 % A
% Cys: 0 0 0 0 8 0 0 8 0 0 0 0 0 0 0 % C
% Asp: 15 8 15 0 0 8 0 0 15 0 0 0 8 0 8 % D
% Glu: 8 8 0 15 0 0 0 8 29 0 8 0 15 8 8 % E
% Phe: 8 8 0 0 0 0 0 0 0 0 8 0 8 0 8 % F
% Gly: 8 36 8 8 0 8 0 0 0 0 0 0 0 22 8 % G
% His: 0 8 0 36 0 22 8 15 0 0 0 0 8 0 0 % H
% Ile: 15 0 0 0 36 0 15 0 8 0 0 0 8 8 0 % I
% Lys: 0 0 8 0 15 0 8 0 0 15 15 8 8 0 36 % K
% Leu: 0 15 0 0 8 8 8 0 15 8 0 29 0 0 15 % L
% Met: 0 0 0 0 0 0 0 0 8 0 0 0 0 8 0 % M
% Asn: 0 0 15 15 0 0 0 0 0 0 8 15 15 8 0 % N
% Pro: 8 0 0 0 8 8 0 0 0 0 0 0 8 0 0 % P
% Gln: 0 0 15 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 8 0 8 0 0 0 0 0 36 29 29 8 8 15 % R
% Ser: 0 8 29 22 15 0 15 0 15 15 0 8 8 15 0 % S
% Thr: 29 0 15 0 8 8 0 0 0 8 8 0 8 0 8 % T
% Val: 15 0 0 0 0 15 50 22 0 8 22 0 0 15 0 % V
% Trp: 0 0 0 0 0 0 0 8 0 0 8 0 0 0 0 % W
% Tyr: 0 8 0 0 0 15 0 43 15 15 0 8 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _