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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: H1FX All Species: 8.48
Human Site: S39 Identified Species: 16.97
UniProt: Q92522 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92522 NP_006017.1 213 22487 S39 P S K K R K N S K K K N Q P G
Chimpanzee Pan troglodytes XP_526304 567 60025 S356 P S K K R K N S K K K N Q P G
Rhesus Macaque Macaca mulatta P40286 208 22075 A39 L T S A S R K A P N L S V S K
Dog Lupus familis XP_541741 213 22389 N39 P S K K K K N N K K K N Q P G
Cat Felis silvestris
Mouse Mus musculus P10922 194 20842 A34 K Y S D M I V A A I Q A E K N
Rat Rattus norvegicus P15865 219 21969 S41 K A S G P P V S E L I T K A V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512226 230 24085 N47 P S K K K K N N K K K N Q P G
Chicken Gallus gallus P09987 218 21863 T42 K P A G P S V T E L I T K A V
Frog Xenopus laevis P06893 220 22422 P39 G G A K A K K P S G P S A S E
Zebra Danio Brachydanio rerio NP_954970 192 20694 K32 V A A S P A K K K K K K S K G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P02255 256 26341 A40 A G T K A K K A S A T P S H P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus P15869 211 22150 S39 L K E R G G S S A Q A I R K Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 36.3 30 89.1 N.A. 28.6 37.4 N.A. 72.1 33.4 34 48.3 N.A. 28.5 N.A. N.A. 24.8
Protein Similarity: 100 36.5 45.5 92 N.A. 40.3 49.7 N.A. 80.4 46.3 49.5 58.6 N.A. 41.7 N.A. N.A. 37.5
P-Site Identity: 100 100 0 86.6 N.A. 0 6.6 N.A. 86.6 0 13.3 26.6 N.A. 13.3 N.A. N.A. 6.6
P-Site Similarity: 100 100 26.6 100 N.A. 20 26.6 N.A. 100 20 20 33.3 N.A. 20 N.A. N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 17 25 9 17 9 0 25 17 9 9 9 9 17 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 9 0 0 0 0 0 17 0 0 0 9 0 9 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 9 17 0 17 9 9 0 0 0 9 0 0 0 0 42 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % H
% Ile: 0 0 0 0 0 9 0 0 0 9 17 9 0 0 0 % I
% Lys: 25 9 34 50 17 50 34 9 42 42 42 9 17 25 9 % K
% Leu: 17 0 0 0 0 0 0 0 0 17 9 0 0 0 0 % L
% Met: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 34 17 0 9 0 34 0 0 9 % N
% Pro: 34 9 0 0 25 9 0 9 9 0 9 9 0 34 9 % P
% Gln: 0 0 0 0 0 0 0 0 0 9 9 0 34 0 0 % Q
% Arg: 0 0 0 9 17 9 0 0 0 0 0 0 9 0 0 % R
% Ser: 0 34 25 9 9 9 9 34 17 0 0 17 17 17 0 % S
% Thr: 0 9 9 0 0 0 0 9 0 0 9 17 0 0 0 % T
% Val: 9 0 0 0 0 0 25 0 0 0 0 0 9 0 17 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _