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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: H1FX All Species: 15.76
Human Site: S65 Identified Species: 31.52
UniProt: Q92522 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92522 NP_006017.1 213 22487 S65 R L G E R N G S S L A K I Y T
Chimpanzee Pan troglodytes XP_526304 567 60025 S382 R L G E R N G S S L A K I Y T
Rhesus Macaque Macaca mulatta P40286 208 22075 A65 R V G M S L A A L K K A L A A
Dog Lupus familis XP_541741 213 22389 S65 R L G E R N G S S L A K I Y T
Cat Felis silvestris
Mouse Mus musculus P10922 194 20842 V60 Y I K S H Y K V G E N A D S Q
Rat Rattus norvegicus P15865 219 21969 A67 A A L K K A L A A A G Y D V E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512226 230 24085 S73 K L G E R N G S S L A K I Y N
Chicken Gallus gallus P09987 218 21863 A68 A A L K K A L A A G G Y D V E
Frog Xenopus laevis P06893 220 22422 A65 R S G V S L A A L K K A L A A
Zebra Danio Brachydanio rerio NP_954970 192 20694 N58 I R T L G E K N G S S L F K I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P02255 256 26341 S66 N L K E R G G S S L L A I K K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus P15869 211 22150 A65 Q A I F I K R A L I T G V E K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 36.3 30 89.1 N.A. 28.6 37.4 N.A. 72.1 33.4 34 48.3 N.A. 28.5 N.A. N.A. 24.8
Protein Similarity: 100 36.5 45.5 92 N.A. 40.3 49.7 N.A. 80.4 46.3 49.5 58.6 N.A. 41.7 N.A. N.A. 37.5
P-Site Identity: 100 100 13.3 100 N.A. 0 0 N.A. 86.6 0 13.3 0 N.A. 53.3 N.A. N.A. 0
P-Site Similarity: 100 100 33.3 100 N.A. 6.6 26.6 N.A. 93.3 26.6 26.6 13.3 N.A. 53.3 N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 25 0 0 0 17 17 42 17 9 34 34 0 17 17 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 25 0 0 % D
% Glu: 0 0 0 42 0 9 0 0 0 9 0 0 0 9 17 % E
% Phe: 0 0 0 9 0 0 0 0 0 0 0 0 9 0 0 % F
% Gly: 0 0 50 0 9 9 42 0 17 9 17 9 0 0 0 % G
% His: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 9 9 0 9 0 0 0 0 9 0 0 42 0 9 % I
% Lys: 9 0 17 17 17 9 17 0 0 17 17 34 0 17 17 % K
% Leu: 0 42 17 9 0 17 17 0 25 42 9 9 17 0 0 % L
% Met: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 9 0 0 0 0 34 0 9 0 0 9 0 0 0 9 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % Q
% Arg: 42 9 0 0 42 0 9 0 0 0 0 0 0 0 0 % R
% Ser: 0 9 0 9 17 0 0 42 42 9 9 0 0 9 0 % S
% Thr: 0 0 9 0 0 0 0 0 0 0 9 0 0 0 25 % T
% Val: 0 9 0 9 0 0 0 9 0 0 0 0 9 17 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 0 0 0 9 0 0 0 0 0 17 0 34 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _