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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: H1FX All Species: 11.82
Human Site: T135 Identified Species: 23.64
UniProt: Q92522 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.36
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92522 NP_006017.1 213 22487 T135 R G A P A A A T A P A P T A H
Chimpanzee Pan troglodytes XP_526304 567 60025 T452 R G A P A A A T A P A P T A Q
Rhesus Macaque Macaca mulatta P40286 208 22075 K131 A N K S A S A K T K K L V L S
Dog Lupus familis XP_541741 213 22389 T135 R G A T A A A T A P A P A A H
Cat Felis silvestris
Mouse Mus musculus P10922 194 20842 A123 K V A T P K K A A K P K K A A
Rat Rattus norvegicus P15865 219 21969 T146 K K A T G T A T P K K S T K K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512226 230 24085 S148 G G T S D R K S S A S S S S H
Chicken Gallus gallus P09987 218 21863 K134 K P K K P A A K K P A A A A K
Frog Xenopus laevis P06893 220 22422 A139 A K K T A A G A K K A P K S P
Zebra Danio Brachydanio rerio NP_954970 192 20694 K121 K K L E K K P K K A A S K K A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P02255 256 26341 V145 K K V Q S K K V A S K K I G V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus P15869 211 22150 K137 K E K L A A K K A S K K T T K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 36.3 30 89.1 N.A. 28.6 37.4 N.A. 72.1 33.4 34 48.3 N.A. 28.5 N.A. N.A. 24.8
Protein Similarity: 100 36.5 45.5 92 N.A. 40.3 49.7 N.A. 80.4 46.3 49.5 58.6 N.A. 41.7 N.A. N.A. 37.5
P-Site Identity: 100 93.3 13.3 86.6 N.A. 20 26.6 N.A. 13.3 33.3 26.6 6.6 N.A. 6.6 N.A. N.A. 26.6
P-Site Similarity: 100 93.3 20 86.6 N.A. 26.6 33.3 N.A. 46.6 40 33.3 13.3 N.A. 20 N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 0 42 0 50 50 50 17 50 17 50 9 17 42 17 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 9 0 9 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 9 34 0 0 9 0 9 0 0 0 0 0 0 9 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 25 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % I
% Lys: 50 34 34 9 9 25 34 34 25 34 34 25 25 17 25 % K
% Leu: 0 0 9 9 0 0 0 0 0 0 0 9 0 9 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 9 0 17 17 0 9 0 9 34 9 34 0 0 9 % P
% Gln: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 9 % Q
% Arg: 25 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 17 9 9 0 9 9 17 9 25 9 17 9 % S
% Thr: 0 0 9 34 0 9 0 34 9 0 0 0 34 9 0 % T
% Val: 0 9 9 0 0 0 0 9 0 0 0 0 9 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _