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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CPT1B All Species: 16.36
Human Site: S461 Identified Species: 32.73
UniProt: Q92523 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92523 NP_001138607.1 772 87801 S461 D K S F T L I S F K N G Q L G
Chimpanzee Pan troglodytes XP_525636 843 95334 S532 D K S F T L I S F K N G Q L G
Rhesus Macaque Macaca mulatta XP_001116383 769 87263 A473 L N A E H A W A D A P I I G H
Dog Lupus familis XP_538305 772 87798 A461 D K S F T V I A F K N G Q L G
Cat Felis silvestris
Mouse Mus musculus Q924X2 772 88199 S461 D K S F T L I S C K N G L L G
Rat Rattus norvegicus Q63704 772 88198 S461 D K S F T L I S C K N G Q L G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90YJ9 640 72605 Q384 W K C S P E I Q A H L A S S A
Frog Xenopus laevis Q7ZXE1 659 74538 S403 R P A I S P E S C S A P V D S
Zebra Danio Brachydanio rerio B2ZGJ1 637 71821 T380 K C S P D I Q T F L S A S A D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P07668 721 81310 E439 E K I Y K K I E E H P D E D N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P32756 627 71299 N371 F K S K M V W N D V R N V H P
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32796 670 77223 S414 R K V I T P S S T V A M K P M
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91 90.1 90.6 N.A. 87 86 N.A. N.A. 23.7 24.3 23.8 N.A. 22.1 N.A. 21.7 N.A.
Protein Similarity: 100 91.3 91.9 96.5 N.A. 94 92.7 N.A. N.A. 41.1 41.8 40.7 N.A. 39.3 N.A. 38.2 N.A.
P-Site Identity: 100 100 0 86.6 N.A. 86.6 93.3 N.A. N.A. 13.3 6.6 13.3 N.A. 13.3 N.A. 13.3 N.A.
P-Site Similarity: 100 100 13.3 100 N.A. 86.6 93.3 N.A. N.A. 13.3 20 33.3 N.A. 33.3 N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 38.9 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 20 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 17 0 0 9 0 17 9 9 17 17 0 9 9 % A
% Cys: 0 9 9 0 0 0 0 0 25 0 0 0 0 0 0 % C
% Asp: 42 0 0 0 9 0 0 0 17 0 0 9 0 17 9 % D
% Glu: 9 0 0 9 0 9 9 9 9 0 0 0 9 0 0 % E
% Phe: 9 0 0 42 0 0 0 0 34 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 42 0 9 42 % G
% His: 0 0 0 0 9 0 0 0 0 17 0 0 0 9 9 % H
% Ile: 0 0 9 17 0 9 59 0 0 0 0 9 9 0 0 % I
% Lys: 9 75 0 9 9 9 0 0 0 42 0 0 9 0 0 % K
% Leu: 9 0 0 0 0 34 0 0 0 9 9 0 9 42 0 % L
% Met: 0 0 0 0 9 0 0 0 0 0 0 9 0 0 9 % M
% Asn: 0 9 0 0 0 0 0 9 0 0 42 9 0 0 9 % N
% Pro: 0 9 0 9 9 17 0 0 0 0 17 9 0 9 9 % P
% Gln: 0 0 0 0 0 0 9 9 0 0 0 0 34 0 0 % Q
% Arg: 17 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % R
% Ser: 0 0 59 9 9 0 9 50 0 9 9 0 17 9 9 % S
% Thr: 0 0 0 0 50 0 0 9 9 0 0 0 0 0 0 % T
% Val: 0 0 9 0 0 17 0 0 0 17 0 0 17 0 0 % V
% Trp: 9 0 0 0 0 0 17 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _