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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CPT1B
All Species:
22.12
Human Site:
Y243
Identified Species:
44.24
UniProt:
Q92523
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92523
NP_001138607.1
772
87801
Y243
D
W
W
E
E
Y
I
Y
L
R
G
R
S
P
L
Chimpanzee
Pan troglodytes
XP_525636
843
95334
Y314
D
W
W
E
E
Y
I
Y
L
R
G
R
S
P
L
Rhesus Macaque
Macaca mulatta
XP_001116383
769
87263
Y281
D
W
W
E
E
Y
I
Y
L
R
G
R
S
P
L
Dog
Lupus familis
XP_538305
772
87798
Y243
D
W
W
E
E
Y
V
Y
L
R
S
R
A
P
L
Cat
Felis silvestris
Mouse
Mus musculus
Q924X2
772
88199
Y243
D
W
W
E
E
Y
V
Y
L
R
S
R
S
P
L
Rat
Rattus norvegicus
Q63704
772
88198
Y243
D
W
W
E
E
Y
V
Y
L
R
G
R
S
P
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90YJ9
640
72605
E192
Q
K
S
C
V
M
P
E
P
E
H
I
I
V
A
Frog
Xenopus laevis
Q7ZXE1
659
74538
A211
Y
G
A
Y
M
V
N
A
Y
P
L
D
M
S
Q
Zebra Danio
Brachydanio rerio
B2ZGJ1
637
71821
P188
K
S
T
V
M
P
E
P
E
H
I
I
V
A
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07668
721
81310
K243
S
C
R
R
P
G
V
K
Q
D
S
Q
F
L
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P32756
627
71299
R179
V
G
E
D
T
Q
I
R
K
Q
K
T
N
D
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32796
670
77223
R222
S
L
M
F
N
T
S
R
L
P
G
K
P
E
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91
90.1
90.6
N.A.
87
86
N.A.
N.A.
23.7
24.3
23.8
N.A.
22.1
N.A.
21.7
N.A.
Protein Similarity:
100
91.3
91.9
96.5
N.A.
94
92.7
N.A.
N.A.
41.1
41.8
40.7
N.A.
39.3
N.A.
38.2
N.A.
P-Site Identity:
100
100
100
80
N.A.
86.6
86.6
N.A.
N.A.
0
0
0
N.A.
0
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
100
N.A.
N.A.
0
0
0
N.A.
13.3
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
0
0
9
0
0
0
0
9
9
9
% A
% Cys:
0
9
0
9
0
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
50
0
0
9
0
0
0
0
0
9
0
9
0
9
9
% D
% Glu:
0
0
9
50
50
0
9
9
9
9
0
0
0
9
0
% E
% Phe:
0
0
0
9
0
0
0
0
0
0
0
0
9
0
0
% F
% Gly:
0
17
0
0
0
9
0
0
0
0
42
0
0
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
9
9
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
34
0
0
0
9
17
9
0
9
% I
% Lys:
9
9
0
0
0
0
0
9
9
0
9
9
0
0
0
% K
% Leu:
0
9
0
0
0
0
0
0
59
0
9
0
0
9
42
% L
% Met:
0
0
9
0
17
9
0
0
0
0
0
0
9
0
0
% M
% Asn:
0
0
0
0
9
0
9
0
0
0
0
0
9
0
0
% N
% Pro:
0
0
0
0
9
9
9
9
9
17
0
0
9
50
9
% P
% Gln:
9
0
0
0
0
9
0
0
9
9
0
9
0
0
9
% Q
% Arg:
0
0
9
9
0
0
0
17
0
50
0
50
0
0
0
% R
% Ser:
17
9
9
0
0
0
9
0
0
0
25
0
42
9
0
% S
% Thr:
0
0
9
0
9
9
0
0
0
0
0
9
0
0
0
% T
% Val:
9
0
0
9
9
9
34
0
0
0
0
0
9
9
0
% V
% Trp:
0
50
50
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
9
0
50
0
50
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _