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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SHC3
All Species:
18.18
Human Site:
S254
Identified Species:
44.44
UniProt:
Q92529
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92529
NP_058544.3
594
64056
S254
N
H
H
M
R
S
I
S
F
A
S
G
G
D
P
Chimpanzee
Pan troglodytes
XP_520118
594
64067
S254
N
H
H
M
R
S
I
S
F
A
S
G
G
D
P
Rhesus Macaque
Macaca mulatta
XP_001089267
598
64694
S254
N
H
H
M
R
S
I
S
F
A
S
G
G
D
P
Dog
Lupus familis
XP_533553
444
48696
G139
H
I
L
E
C
C
D
G
L
A
Q
D
V
I
G
Cat
Felis silvestris
Mouse
Mus musculus
Q61120
474
52188
L169
I
L
E
C
C
D
G
L
A
Q
D
V
I
G
S
Rat
Rattus norvegicus
O70143
594
64082
S254
N
H
H
M
R
S
I
S
F
A
S
G
G
D
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512200
548
59956
E243
Q
R
A
C
H
I
L
E
C
C
E
A
Q
S
V
Chicken
Gallus gallus
XP_428819
632
69780
S276
N
H
H
M
Q
S
I
S
F
A
S
G
G
D
P
Frog
Xenopus laevis
Q8AY68
465
51711
E160
G
G
D
P
D
T
A
E
Y
V
A
Y
V
A
K
Zebra Danio
Brachydanio rerio
XP_002665883
393
43159
Q88
E
C
S
D
G
L
A
Q
D
V
I
S
T
I
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.4
67.5
N.A.
73
91
N.A.
47.8
67.7
45.2
42.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
97.8
70.3
N.A.
75.5
93.9
N.A.
61.2
76.9
57.9
49.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
0
100
N.A.
0
93.3
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
0
100
N.A.
6.6
100
20
0
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
20
0
10
60
10
10
0
10
0
% A
% Cys:
0
10
0
20
20
10
0
0
10
10
0
0
0
0
0
% C
% Asp:
0
0
10
10
10
10
10
0
10
0
10
10
0
50
0
% D
% Glu:
10
0
10
10
0
0
0
20
0
0
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
50
0
0
0
0
0
0
% F
% Gly:
10
10
0
0
10
0
10
10
0
0
0
50
50
10
20
% G
% His:
10
50
50
0
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
10
0
0
0
10
50
0
0
0
10
0
10
20
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% K
% Leu:
0
10
10
0
0
10
10
10
10
0
0
0
0
0
0
% L
% Met:
0
0
0
50
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
50
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
50
% P
% Gln:
10
0
0
0
10
0
0
10
0
10
10
0
10
0
0
% Q
% Arg:
0
10
0
0
40
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
10
0
0
50
0
50
0
0
50
10
0
10
10
% S
% Thr:
0
0
0
0
0
10
0
0
0
0
0
0
10
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
20
0
10
20
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _