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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PIGC All Species: 38.79
Human Site: T141 Identified Species: 77.58
UniProt: Q92535 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92535 NP_002633.1 297 33583 T141 S P V L K T L T E S V S T D T
Chimpanzee Pan troglodytes XP_001147341 297 33532 T141 S P V L K T L T E S V S T D T
Rhesus Macaque Macaca mulatta XP_001100450 297 33539 T141 S P V L K T L T E S V S T D T
Dog Lupus familis XP_537194 297 33536 T141 S P V L K T L T E S V S T D T
Cat Felis silvestris
Mouse Mus musculus Q9CXR4 297 33705 T141 S P V L K T L T E S V S T D T
Rat Rattus norvegicus Q5PQQ4 297 33648 T141 S P V L K T L T E S V S T D T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515114 345 38162 T189 S P V L K T L T E S V S T D T
Chicken Gallus gallus XP_422231 297 33272 T141 S P V L K T L T E S I S T D T
Frog Xenopus laevis NP_001088459 319 35737 T163 S P V L K T L T E S I S T D T
Zebra Danio Brachydanio rerio NP_998426 293 32401 V142 L K T L T E S V S T D T V Y A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001192159 218 24880 L78 R L S P S S L L C V S G W L T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P46961 280 32559 S138 S L S K T T A S D S I W T L S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 98.3 95.9 N.A. 93.5 93.2 N.A. 74.1 79.8 71.7 53.5 N.A. N.A. N.A. N.A. 36.3
Protein Similarity: 100 99.6 99.3 98.9 N.A. 96.6 95.9 N.A. 80.5 86.5 81.8 69.6 N.A. N.A. N.A. N.A. 49.8
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 93.3 93.3 6.6 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 100 20 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 41.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 9 0 9 0 0 75 0 % D
% Glu: 0 0 0 0 0 9 0 0 75 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 25 0 0 0 0 % I
% Lys: 0 9 0 9 75 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 9 17 0 84 0 0 84 9 0 0 0 0 0 17 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 75 0 9 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 84 0 17 0 9 9 9 9 9 84 9 75 0 0 9 % S
% Thr: 0 0 9 0 17 84 0 75 0 9 0 9 84 0 84 % T
% Val: 0 0 75 0 0 0 0 9 0 9 59 0 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 9 9 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _