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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PIGC All Species: 30.91
Human Site: T224 Identified Species: 61.82
UniProt: Q92535 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92535 NP_002633.1 297 33583 T224 Q K K L K A C T P R S Y V G V
Chimpanzee Pan troglodytes XP_001147341 297 33532 T224 Q K K L K A C T P R S Y V G V
Rhesus Macaque Macaca mulatta XP_001100450 297 33539 T224 Q K K L K A C T P R S Y V G V
Dog Lupus familis XP_537194 297 33536 T224 Q K K L K A C T P C S Y V G V
Cat Felis silvestris
Mouse Mus musculus Q9CXR4 297 33705 T224 Q K K L K A Y T P R S Y V G V
Rat Rattus norvegicus Q5PQQ4 297 33648 T224 Q K K L K A Y T P R S Y V G V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515114 345 38162 A272 Q K K L K A R A P P A Y V A L
Chicken Gallus gallus XP_422231 297 33272 T224 Q K K L K A R T P C C Y V G V
Frog Xenopus laevis NP_001088459 319 35737 T246 Q R K L R A N T P R T Y I G V
Zebra Danio Brachydanio rerio NP_998426 293 32401 A220 L H R V R E K A D W S F P W A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001192159 218 24880 T156 Q L F A L W P T L R K R L K K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P46961 280 32559 P216 S V T N K V V P I I S N I I V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 98.3 95.9 N.A. 93.5 93.2 N.A. 74.1 79.8 71.7 53.5 N.A. N.A. N.A. N.A. 36.3
Protein Similarity: 100 99.6 99.3 98.9 N.A. 96.6 95.9 N.A. 80.5 86.5 81.8 69.6 N.A. N.A. N.A. N.A. 49.8
P-Site Identity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 60 80 66.6 6.6 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 73.3 80 93.3 33.3 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 41.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 20 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 0 75 0 17 0 0 9 0 0 9 9 % A
% Cys: 0 0 0 0 0 0 34 0 0 17 9 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 9 0 0 0 0 0 0 0 0 9 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 67 0 % G
% His: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 9 9 0 0 17 9 0 % I
% Lys: 0 67 75 0 75 0 9 0 0 0 9 0 0 9 9 % K
% Leu: 9 9 0 75 9 0 0 0 9 0 0 0 9 0 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 9 0 0 9 0 0 0 0 9 0 0 0 % N
% Pro: 0 0 0 0 0 0 9 9 75 9 0 0 9 0 0 % P
% Gln: 84 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 9 9 0 17 0 17 0 0 59 0 9 0 0 0 % R
% Ser: 9 0 0 0 0 0 0 0 0 0 67 0 0 0 0 % S
% Thr: 0 0 9 0 0 0 0 75 0 0 9 0 0 0 0 % T
% Val: 0 9 0 9 0 9 9 0 0 0 0 0 67 0 75 % V
% Trp: 0 0 0 0 0 9 0 0 0 9 0 0 0 9 0 % W
% Tyr: 0 0 0 0 0 0 17 0 0 0 0 75 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _