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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC7A6 All Species: 14.85
Human Site: S155 Identified Species: 29.7
UniProt: Q92536 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92536 NP_001070253.1 515 56828 S155 A N Y I I Q P S F P S C D P P
Chimpanzee Pan troglodytes XP_001146701 634 69017 S274 A N Y I I Q P S F P S C D P P
Rhesus Macaque Macaca mulatta XP_001091215 539 59124 I172 L V T Q L K R I Q S L P L M G
Dog Lupus familis XP_851473 521 57417 S154 A N Y I I Q P S F P T C D P P
Cat Felis silvestris
Mouse Mus musculus Q8BGK6 515 56752 S155 A N Y I I K P S F P T C D P P
Rat Rattus norvegicus Q9R0S5 512 55623 P157 L F P S C G A P Y A A G R L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505546 514 56448 V154 A N Y I V Q P V F P S C E P P
Chicken Gallus gallus XP_001231337 518 57043 F158 A N Y I V Q P F F P S C D P P
Frog Xenopus laevis A1L3M3 510 55983 P157 V F P S C N P P Y M A S R L I
Zebra Danio Brachydanio rerio Q59I64 468 51216 F118 N Y L V Q P L F P T C E P P Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790356 509 55459 Q159 T F A Y Y V V Q P F Y P T E D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P50276 574 63203 T169 N T A I M F L T A A D T E V T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 81.2 52.5 89.2 N.A. 89.1 69.9 N.A. 79.4 76.4 72.6 71.6 N.A. N.A. N.A. N.A. 46.2
Protein Similarity: 100 81.2 60.6 93.4 N.A. 94.7 85.6 N.A. 87.9 87 87.7 82.9 N.A. N.A. N.A. N.A. 67.1
P-Site Identity: 100 100 0 93.3 N.A. 86.6 0 N.A. 80 86.6 6.6 6.6 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 13.3 100 N.A. 100 13.3 N.A. 93.3 93.3 20 13.3 N.A. N.A. N.A. N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 43.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 50 0 17 0 0 0 9 0 9 17 17 0 0 0 0 % A
% Cys: 0 0 0 0 17 0 0 0 0 0 9 50 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 9 0 42 0 9 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 9 17 9 0 % E
% Phe: 0 25 0 0 0 9 0 17 50 9 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 9 0 0 0 0 0 9 0 0 9 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 59 34 0 0 9 0 0 0 0 0 0 9 % I
% Lys: 0 0 0 0 0 17 0 0 0 0 0 0 0 0 0 % K
% Leu: 17 0 9 0 9 0 17 0 0 0 9 0 9 17 9 % L
% Met: 0 0 0 0 9 0 0 0 0 9 0 0 0 9 0 % M
% Asn: 17 50 0 0 0 9 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 17 0 0 9 59 17 17 50 0 17 9 59 50 % P
% Gln: 0 0 0 9 9 42 0 9 9 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 9 0 0 0 0 0 17 0 0 % R
% Ser: 0 0 0 17 0 0 0 34 0 9 34 9 0 0 0 % S
% Thr: 9 9 9 0 0 0 0 9 0 9 17 9 9 0 9 % T
% Val: 9 9 0 9 17 9 9 9 0 0 0 0 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 50 9 9 0 0 0 17 0 9 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _