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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC7A6
All Species:
30.3
Human Site:
Y470
Identified Species:
60.61
UniProt:
Q92536
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92536
NP_001070253.1
515
56828
Y470
P
F
Y
F
M
G
V
Y
L
P
E
S
R
R
P
Chimpanzee
Pan troglodytes
XP_001146701
634
69017
Y589
P
F
Y
F
M
G
V
Y
L
P
E
S
R
R
P
Rhesus Macaque
Macaca mulatta
XP_001091215
539
59124
Y494
P
F
Y
F
M
G
V
Y
L
P
E
S
Q
R
P
Dog
Lupus familis
XP_851473
521
57417
Y476
P
V
Y
F
V
G
V
Y
L
P
E
S
Q
R
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGK6
515
56752
Y470
P
V
Y
F
L
G
V
Y
L
P
E
S
R
R
P
Rat
Rattus norvegicus
Q9R0S5
512
55623
R465
P
F
Y
F
L
I
I
R
V
P
E
H
K
R
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505546
514
56448
Y469
P
V
Y
V
L
G
V
Y
L
P
V
S
R
R
P
Chicken
Gallus gallus
XP_001231337
518
57043
Y473
P
V
F
F
L
G
V
Y
L
P
A
S
R
R
P
Frog
Xenopus laevis
A1L3M3
510
55983
Y465
P
V
Y
F
M
G
I
Y
L
P
E
S
K
R
P
Zebra Danio
Brachydanio rerio
Q59I64
468
51216
V424
I
A
I
A
L
S
G
V
P
V
Y
F
L
G
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790356
509
55459
T465
T
L
I
G
L
A
I
T
L
T
G
F
P
V
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P50276
574
63203
I496
P
Y
W
I
H
C
V
I
A
W
G
I
F
F
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.2
52.5
89.2
N.A.
89.1
69.9
N.A.
79.4
76.4
72.6
71.6
N.A.
N.A.
N.A.
N.A.
46.2
Protein Similarity:
100
81.2
60.6
93.4
N.A.
94.7
85.6
N.A.
87.9
87
87.7
82.9
N.A.
N.A.
N.A.
N.A.
67.1
P-Site Identity:
100
100
93.3
80
N.A.
86.6
53.3
N.A.
73.3
73.3
80
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
80
N.A.
80
86.6
93.3
6.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
9
0
9
0
0
9
0
9
0
0
0
0
% A
% Cys:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
59
0
0
0
0
% E
% Phe:
0
34
9
67
0
0
0
0
0
0
0
17
9
9
9
% F
% Gly:
0
0
0
9
0
67
9
0
0
0
17
0
0
9
0
% G
% His:
0
0
0
0
9
0
0
0
0
0
0
9
0
0
0
% H
% Ile:
9
0
17
9
0
9
25
9
0
0
0
9
0
0
9
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
17
0
0
% K
% Leu:
0
9
0
0
50
0
0
0
75
0
0
0
9
0
0
% L
% Met:
0
0
0
0
34
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
84
0
0
0
0
0
0
0
9
75
0
0
9
0
75
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
17
0
0
% Q
% Arg:
0
0
0
0
0
0
0
9
0
0
0
0
42
75
0
% R
% Ser:
0
0
0
0
0
9
0
0
0
0
0
67
0
0
0
% S
% Thr:
9
0
0
0
0
0
0
9
0
9
0
0
0
0
0
% T
% Val:
0
42
0
9
9
0
67
9
9
9
9
0
0
9
0
% V
% Trp:
0
0
9
0
0
0
0
0
0
9
0
0
0
0
0
% W
% Tyr:
0
9
67
0
0
0
0
67
0
0
9
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _