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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC7A6 All Species: 30.3
Human Site: Y470 Identified Species: 60.61
UniProt: Q92536 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92536 NP_001070253.1 515 56828 Y470 P F Y F M G V Y L P E S R R P
Chimpanzee Pan troglodytes XP_001146701 634 69017 Y589 P F Y F M G V Y L P E S R R P
Rhesus Macaque Macaca mulatta XP_001091215 539 59124 Y494 P F Y F M G V Y L P E S Q R P
Dog Lupus familis XP_851473 521 57417 Y476 P V Y F V G V Y L P E S Q R P
Cat Felis silvestris
Mouse Mus musculus Q8BGK6 515 56752 Y470 P V Y F L G V Y L P E S R R P
Rat Rattus norvegicus Q9R0S5 512 55623 R465 P F Y F L I I R V P E H K R P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505546 514 56448 Y469 P V Y V L G V Y L P V S R R P
Chicken Gallus gallus XP_001231337 518 57043 Y473 P V F F L G V Y L P A S R R P
Frog Xenopus laevis A1L3M3 510 55983 Y465 P V Y F M G I Y L P E S K R P
Zebra Danio Brachydanio rerio Q59I64 468 51216 V424 I A I A L S G V P V Y F L G I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790356 509 55459 T465 T L I G L A I T L T G F P V Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P50276 574 63203 I496 P Y W I H C V I A W G I F F F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 81.2 52.5 89.2 N.A. 89.1 69.9 N.A. 79.4 76.4 72.6 71.6 N.A. N.A. N.A. N.A. 46.2
Protein Similarity: 100 81.2 60.6 93.4 N.A. 94.7 85.6 N.A. 87.9 87 87.7 82.9 N.A. N.A. N.A. N.A. 67.1
P-Site Identity: 100 100 93.3 80 N.A. 86.6 53.3 N.A. 73.3 73.3 80 0 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 80 N.A. 80 86.6 93.3 6.6 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 43.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 9 0 9 0 0 9 0 9 0 0 0 0 % A
% Cys: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 59 0 0 0 0 % E
% Phe: 0 34 9 67 0 0 0 0 0 0 0 17 9 9 9 % F
% Gly: 0 0 0 9 0 67 9 0 0 0 17 0 0 9 0 % G
% His: 0 0 0 0 9 0 0 0 0 0 0 9 0 0 0 % H
% Ile: 9 0 17 9 0 9 25 9 0 0 0 9 0 0 9 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 17 0 0 % K
% Leu: 0 9 0 0 50 0 0 0 75 0 0 0 9 0 0 % L
% Met: 0 0 0 0 34 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 84 0 0 0 0 0 0 0 9 75 0 0 9 0 75 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 17 0 0 % Q
% Arg: 0 0 0 0 0 0 0 9 0 0 0 0 42 75 0 % R
% Ser: 0 0 0 0 0 9 0 0 0 0 0 67 0 0 0 % S
% Thr: 9 0 0 0 0 0 0 9 0 9 0 0 0 0 0 % T
% Val: 0 42 0 9 9 0 67 9 9 9 9 0 0 9 0 % V
% Trp: 0 0 9 0 0 0 0 0 0 9 0 0 0 0 0 % W
% Tyr: 0 9 67 0 0 0 0 67 0 0 9 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _