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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GBF1 All Species: 17.88
Human Site: S997 Identified Species: 49.17
UniProt: Q92538 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92538 NP_004184.1 1859 206446 S997 E S I E N L P S V F G S N P K
Chimpanzee Pan troglodytes XP_521592 2376 261791 S1514 E S I E N L P S V F G S N P K
Rhesus Macaque Macaca mulatta XP_001104407 1902 211185 S1040 E S I E N L P S V F G S N P K
Dog Lupus familis XP_850976 1872 207719 Q998 E V K Q I E P Q Q A K G L L N
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_421632 1852 206408 T992 E S I E N L P T V F G S N P K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_694714 1873 208801 T1018 E S V E N L P T V F G S N R K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610761 1983 220573 D987 E S W K H I L D L Y L Q L F R
Honey Bee Apis mellifera XP_001123021 1745 194801 R959 H P A E T T A R K R A T E F I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q42510 1451 162600 L697 L S Y S I I M L N T D Q H N V
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 77.9 96.7 95.5 N.A. N.A. N.A. N.A. N.A. 83.4 N.A. 75.2 N.A. 43.2 33.8 N.A. N.A.
Protein Similarity: 100 78 97 97 N.A. N.A. N.A. N.A. N.A. 89.6 N.A. 84.6 N.A. 59.9 51.5 N.A. N.A.
P-Site Identity: 100 100 100 13.3 N.A. N.A. N.A. N.A. N.A. 93.3 N.A. 80 N.A. 13.3 6.6 N.A. N.A.
P-Site Similarity: 100 100 100 20 N.A. N.A. N.A. N.A. N.A. 100 N.A. 93.3 N.A. 53.3 13.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 24.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 40.7 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 12 0 0 0 12 0 0 12 12 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 12 0 0 12 0 0 0 0 % D
% Glu: 78 0 0 67 0 12 0 0 0 0 0 0 12 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 56 0 0 0 23 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 56 12 0 0 0 % G
% His: 12 0 0 0 12 0 0 0 0 0 0 0 12 0 0 % H
% Ile: 0 0 45 0 23 23 0 0 0 0 0 0 0 0 12 % I
% Lys: 0 0 12 12 0 0 0 0 12 0 12 0 0 0 56 % K
% Leu: 12 0 0 0 0 56 12 12 12 0 12 0 23 12 0 % L
% Met: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 56 0 0 0 12 0 0 0 56 12 12 % N
% Pro: 0 12 0 0 0 0 67 0 0 0 0 0 0 45 0 % P
% Gln: 0 0 0 12 0 0 0 12 12 0 0 23 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 12 0 12 0 0 0 12 12 % R
% Ser: 0 78 0 12 0 0 0 34 0 0 0 56 0 0 0 % S
% Thr: 0 0 0 0 12 12 0 23 0 12 0 12 0 0 0 % T
% Val: 0 12 12 0 0 0 0 0 56 0 0 0 0 0 12 % V
% Trp: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 12 0 0 0 0 0 0 12 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _