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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GBF1 All Species: 17.88
Human Site: Y1442 Identified Species: 49.17
UniProt: Q92538 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92538 NP_004184.1 1859 206446 Y1442 K R G K S H K Y D S K G N R F
Chimpanzee Pan troglodytes XP_521592 2376 261791 Y1959 K R G K S H K Y D S K G N R F
Rhesus Macaque Macaca mulatta XP_001104407 1902 211185 Y1485 K R G K S H K Y D S K G N R F
Dog Lupus familis XP_850976 1872 207719 Y1455 K R G K S H K Y D S K G N R F
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_421632 1852 206408 H1431 Q E K R G K S H R H D S K T S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_694714 1873 208801 S1461 K K S H K Y D S K S S R L R K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610761 1983 220573 S1401 Q K S S K K R S E R K P G M A
Honey Bee Apis mellifera XP_001123021 1745 194801 S1335 A H D L A Q L S A I E W S Q C
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q42510 1451 162600 A1066 Y E H I A T I A Q S T V M P C
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 77.9 96.7 95.5 N.A. N.A. N.A. N.A. N.A. 83.4 N.A. 75.2 N.A. 43.2 33.8 N.A. N.A.
Protein Similarity: 100 78 97 97 N.A. N.A. N.A. N.A. N.A. 89.6 N.A. 84.6 N.A. 59.9 51.5 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. N.A. N.A. N.A. N.A. 0 N.A. 20 N.A. 6.6 0 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. N.A. N.A. N.A. N.A. 20 N.A. 33.3 N.A. 33.3 26.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 24.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 40.7 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 0 0 0 23 0 0 12 12 0 0 0 0 0 12 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 23 % C
% Asp: 0 0 12 0 0 0 12 0 45 0 12 0 0 0 0 % D
% Glu: 0 23 0 0 0 0 0 0 12 0 12 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 45 % F
% Gly: 0 0 45 0 12 0 0 0 0 0 0 45 12 0 0 % G
% His: 0 12 12 12 0 45 0 12 0 12 0 0 0 0 0 % H
% Ile: 0 0 0 12 0 0 12 0 0 12 0 0 0 0 0 % I
% Lys: 56 23 12 45 23 23 45 0 12 0 56 0 12 0 12 % K
% Leu: 0 0 0 12 0 0 12 0 0 0 0 0 12 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 12 12 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 45 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 12 0 12 0 % P
% Gln: 23 0 0 0 0 12 0 0 12 0 0 0 0 12 0 % Q
% Arg: 0 45 0 12 0 0 12 0 12 12 0 12 0 56 0 % R
% Ser: 0 0 23 12 45 0 12 34 0 67 12 12 12 0 12 % S
% Thr: 0 0 0 0 0 12 0 0 0 0 12 0 0 12 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0 % W
% Tyr: 12 0 0 0 0 12 0 45 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _