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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SMG7 All Species: 18.48
Human Site: S1067 Identified Species: 45.19
UniProt: Q92540 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92540 NP_775179.1 1137 127282 S1067 Y L S A T S S S E S S W H Q A
Chimpanzee Pan troglodytes XP_514048 1195 133575 S1125 Y L S A T S S S E S S W H Q A
Rhesus Macaque Macaca mulatta XP_001109289 1447 160801 S1340 Y L S A T S S S E S S W H Q A
Dog Lupus familis XP_537157 1072 119777 H1007 S S S E S S W H Q A S T A S G
Cat Felis silvestris
Mouse Mus musculus Q5RJH6 1138 126823 S1068 Y L S A T S S S E S S W H Q A
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516046 1166 130499 S1095 Y L P A T S S S S E S S W H Q
Chicken Gallus gallus XP_422287 1122 125325 S1050 Y L P A T S S S S S E S S W H
Frog Xenopus laevis NP_001086379 1129 126148 P1055 L D Y L S M T P S S E N S W R
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393064 1132 126772 N1065 S K S L E I D N K S N Q S I S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_197441 1059 116987 G994 S G K P E H L G S T G N G L N
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.5 73.2 91.8 N.A. 91.6 N.A. N.A. 89.1 88.7 71.9 N.A. N.A. N.A. 28.3 N.A. N.A.
Protein Similarity: 100 94.9 73.8 93.4 N.A. 93.7 N.A. N.A. 92.5 93.2 82.6 N.A. N.A. N.A. 45.7 N.A. N.A.
P-Site Identity: 100 100 100 20 N.A. 100 N.A. N.A. 53.3 53.3 6.6 N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: 100 100 100 40 N.A. 100 N.A. N.A. 53.3 53.3 20 N.A. N.A. N.A. 40 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 21.1 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 36.8 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 60 0 0 0 0 0 10 0 0 10 0 40 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 0 0 10 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 10 20 0 0 0 40 10 20 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 0 0 0 0 0 10 0 0 10 0 10 0 10 % G
% His: 0 0 0 0 0 10 0 10 0 0 0 0 40 10 10 % H
% Ile: 0 0 0 0 0 10 0 0 0 0 0 0 0 10 0 % I
% Lys: 0 10 10 0 0 0 0 0 10 0 0 0 0 0 0 % K
% Leu: 10 60 0 20 0 0 10 0 0 0 0 0 0 10 0 % L
% Met: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 10 0 0 10 20 0 0 10 % N
% Pro: 0 0 20 10 0 0 0 10 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 10 0 0 10 0 40 10 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % R
% Ser: 30 10 60 0 20 70 60 60 40 70 60 20 30 10 10 % S
% Thr: 0 0 0 0 60 0 10 0 0 10 0 10 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 10 0 0 0 0 40 10 20 0 % W
% Tyr: 60 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _