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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMG7
All Species:
20.61
Human Site:
S408
Identified Species:
50.37
UniProt:
Q92540
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92540
NP_775179.1
1137
127282
S408
H
P
H
E
E
D
L
S
S
I
S
A
T
P
L
Chimpanzee
Pan troglodytes
XP_514048
1195
133575
S416
H
P
H
E
E
D
L
S
S
I
S
A
T
P
L
Rhesus Macaque
Macaca mulatta
XP_001109289
1447
160801
S677
H
P
H
E
E
D
L
S
S
T
S
A
T
P
L
Dog
Lupus familis
XP_537157
1072
119777
P384
S
L
L
N
S
F
H
P
H
E
E
D
L
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q5RJH6
1138
126823
S407
H
P
R
E
D
D
L
S
N
T
N
A
T
P
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516046
1166
130499
S435
Q
P
H
E
E
D
L
S
N
T
N
A
T
P
L
Chicken
Gallus gallus
XP_422287
1122
125325
N391
H
E
E
D
L
S
N
N
N
A
T
P
L
P
E
Frog
Xenopus laevis
NP_001086379
1129
126148
S408
H
V
L
D
E
D
V
S
S
A
N
M
L
P
L
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393064
1132
126772
T413
Q
N
C
V
I
D
F
T
Y
D
Q
Y
I
K
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_197441
1059
116987
D371
T
L
G
I
D
T
S
D
S
A
L
F
I
V
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.5
73.2
91.8
N.A.
91.6
N.A.
N.A.
89.1
88.7
71.9
N.A.
N.A.
N.A.
28.3
N.A.
N.A.
Protein Similarity:
100
94.9
73.8
93.4
N.A.
93.7
N.A.
N.A.
92.5
93.2
82.6
N.A.
N.A.
N.A.
45.7
N.A.
N.A.
P-Site Identity:
100
100
93.3
0
N.A.
66.6
N.A.
N.A.
73.3
13.3
46.6
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
100
100
93.3
0
N.A.
86.6
N.A.
N.A.
86.6
40
66.6
N.A.
N.A.
N.A.
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
30
0
50
0
0
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
20
20
70
0
10
0
10
0
10
0
0
0
% D
% Glu:
0
10
10
50
50
0
0
0
0
10
10
0
0
0
10
% E
% Phe:
0
0
0
0
0
10
10
0
0
0
0
10
0
0
0
% F
% Gly:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
60
0
40
0
0
0
10
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
10
0
0
0
0
20
0
0
20
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% K
% Leu:
0
20
20
0
10
0
50
0
0
0
10
0
30
0
60
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
10
0
10
0
0
10
10
30
0
30
0
0
0
0
% N
% Pro:
0
50
0
0
0
0
0
10
0
0
0
10
0
70
0
% P
% Gln:
20
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% Q
% Arg:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
10
% R
% Ser:
10
0
0
0
10
10
10
60
50
0
30
0
0
10
10
% S
% Thr:
10
0
0
0
0
10
0
10
0
30
10
0
50
0
0
% T
% Val:
0
10
0
10
0
0
10
0
0
0
0
0
0
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _