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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SMG7 All Species: 12.73
Human Site: S530 Identified Species: 31.11
UniProt: Q92540 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92540 NP_775179.1 1137 127282 S530 L K S V L S T S R N L S N N C
Chimpanzee Pan troglodytes XP_514048 1195 133575 S538 L K S V L S T S R N L S N N C
Rhesus Macaque Macaca mulatta XP_001109289 1447 160801 S799 L K S V L S T S R N L S N N C
Dog Lupus familis XP_537157 1072 119777 T491 E N L I L P E T S M I E S L S
Cat Felis silvestris
Mouse Mus musculus Q5RJH6 1138 126823 G529 L K S V L S T G R N P S N S C
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516046 1166 130499 G557 L K S V L S T G R N L S N N C
Chicken Gallus gallus XP_422287 1122 125325 S513 S V L S S G R S L S N C D S G
Frog Xenopus laevis NP_001086379 1129 126148 S525 E G S P G L K S V L S T G R S
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393064 1132 126772 A534 S P V L S E S A S S K G S T D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_197441 1059 116987 V478 S F W N Q F V V F F N Q V L S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.5 73.2 91.8 N.A. 91.6 N.A. N.A. 89.1 88.7 71.9 N.A. N.A. N.A. 28.3 N.A. N.A.
Protein Similarity: 100 94.9 73.8 93.4 N.A. 93.7 N.A. N.A. 92.5 93.2 82.6 N.A. N.A. N.A. 45.7 N.A. N.A.
P-Site Identity: 100 100 100 6.6 N.A. 80 N.A. N.A. 93.3 6.6 13.3 N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 100 100 100 33.3 N.A. 86.6 N.A. N.A. 93.3 26.6 20 N.A. N.A. N.A. 33.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 21.1 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 36.8 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 0 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 50 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 10 % D
% Glu: 20 0 0 0 0 10 10 0 0 0 0 10 0 0 0 % E
% Phe: 0 10 0 0 0 10 0 0 10 10 0 0 0 0 0 % F
% Gly: 0 10 0 0 10 10 0 20 0 0 0 10 10 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 10 0 0 0 0 0 0 10 0 0 0 0 % I
% Lys: 0 50 0 0 0 0 10 0 0 0 10 0 0 0 0 % K
% Leu: 50 0 20 10 60 10 0 0 10 10 40 0 0 20 0 % L
% Met: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % M
% Asn: 0 10 0 10 0 0 0 0 0 50 20 0 50 40 0 % N
% Pro: 0 10 0 10 0 10 0 0 0 0 10 0 0 0 0 % P
% Gln: 0 0 0 0 10 0 0 0 0 0 0 10 0 0 0 % Q
% Arg: 0 0 0 0 0 0 10 0 50 0 0 0 0 10 0 % R
% Ser: 30 0 60 10 20 50 10 50 20 20 10 50 20 20 30 % S
% Thr: 0 0 0 0 0 0 50 10 0 0 0 10 0 10 0 % T
% Val: 0 10 10 50 0 0 10 10 10 0 0 0 10 0 0 % V
% Trp: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _