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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMG7
All Species:
18.18
Human Site:
T546
Identified Species:
44.44
UniProt:
Q92540
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92540
NP_775179.1
1137
127282
T546
T
G
E
K
P
V
V
T
F
K
E
N
I
K
T
Chimpanzee
Pan troglodytes
XP_514048
1195
133575
T554
T
G
E
K
P
V
V
T
F
K
E
N
I
K
P
Rhesus Macaque
Macaca mulatta
XP_001109289
1447
160801
T815
T
G
E
K
P
V
V
T
F
K
E
N
I
K
P
Dog
Lupus familis
XP_537157
1072
119777
S507
D
G
N
P
G
L
K
S
V
L
S
T
G
R
N
Cat
Felis silvestris
Mouse
Mus musculus
Q5RJH6
1138
126823
T545
S
G
E
K
P
V
V
T
F
K
E
N
I
K
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516046
1166
130499
T573
T
G
E
K
P
M
V
T
F
K
E
N
I
K
P
Chicken
Gallus gallus
XP_422287
1122
125325
E529
K
P
M
V
T
F
K
E
N
I
K
P
R
E
M
Frog
Xenopus laevis
NP_001086379
1129
126148
P541
S
C
D
T
N
E
K
P
V
V
T
F
K
E
N
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393064
1132
126772
D550
D
I
L
E
H
A
L
D
K
R
I
G
I
L
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_197441
1059
116987
V494
G
P
T
F
I
D
D
V
E
D
E
T
C
F
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.5
73.2
91.8
N.A.
91.6
N.A.
N.A.
89.1
88.7
71.9
N.A.
N.A.
N.A.
28.3
N.A.
N.A.
Protein Similarity:
100
94.9
73.8
93.4
N.A.
93.7
N.A.
N.A.
92.5
93.2
82.6
N.A.
N.A.
N.A.
45.7
N.A.
N.A.
P-Site Identity:
100
93.3
93.3
6.6
N.A.
86.6
N.A.
N.A.
86.6
0
0
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
100
93.3
93.3
26.6
N.A.
93.3
N.A.
N.A.
93.3
13.3
20
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
20
0
10
0
0
10
10
10
0
10
0
0
0
0
0
% D
% Glu:
0
0
50
10
0
10
0
10
10
0
60
0
0
20
0
% E
% Phe:
0
0
0
10
0
10
0
0
50
0
0
10
0
10
0
% F
% Gly:
10
60
0
0
10
0
0
0
0
0
0
10
10
0
0
% G
% His:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
10
0
0
0
0
10
10
0
60
0
0
% I
% Lys:
10
0
0
50
0
0
30
0
10
50
10
0
10
50
10
% K
% Leu:
0
0
10
0
0
10
10
0
0
10
0
0
0
10
0
% L
% Met:
0
0
10
0
0
10
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
10
0
10
0
0
0
10
0
0
50
0
0
20
% N
% Pro:
0
20
0
10
50
0
0
10
0
0
0
10
0
0
40
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
10
0
0
10
10
0
% R
% Ser:
20
0
0
0
0
0
0
10
0
0
10
0
0
0
10
% S
% Thr:
40
0
10
10
10
0
0
50
0
0
10
20
0
0
10
% T
% Val:
0
0
0
10
0
40
50
10
20
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _