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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMG7
All Species:
20.61
Human Site:
T635
Identified Species:
50.37
UniProt:
Q92540
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92540
NP_775179.1
1137
127282
T635
E
A
R
K
T
P
V
T
Q
T
P
T
Q
A
S
Chimpanzee
Pan troglodytes
XP_514048
1195
133575
T643
E
A
R
K
T
P
V
T
Q
T
P
T
Q
A
S
Rhesus Macaque
Macaca mulatta
XP_001109289
1447
160801
S904
P
V
A
F
S
M
G
S
G
Y
T
F
P
A
G
Dog
Lupus familis
XP_537157
1072
119777
S596
G
A
F
P
P
L
P
S
R
P
G
F
P
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q5RJH6
1138
126823
Y634
A
F
S
M
G
S
G
Y
T
F
P
A
G
V
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516046
1166
130499
T662
E
A
R
K
T
P
V
T
P
T
P
S
Q
A
N
Chicken
Gallus gallus
XP_422287
1122
125325
T618
E
A
R
K
T
P
V
T
Q
T
P
S
Q
A
S
Frog
Xenopus laevis
NP_001086379
1129
126148
T630
E
S
R
K
T
A
V
T
T
T
S
S
P
S
S
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393064
1132
126772
S639
I
S
I
S
P
T
K
S
V
T
P
S
G
N
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_197441
1059
116987
K583
H
V
Y
F
D
S
K
K
K
K
F
L
V
G
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.5
73.2
91.8
N.A.
91.6
N.A.
N.A.
89.1
88.7
71.9
N.A.
N.A.
N.A.
28.3
N.A.
N.A.
Protein Similarity:
100
94.9
73.8
93.4
N.A.
93.7
N.A.
N.A.
92.5
93.2
82.6
N.A.
N.A.
N.A.
45.7
N.A.
N.A.
P-Site Identity:
100
100
6.6
6.6
N.A.
13.3
N.A.
N.A.
80
93.3
53.3
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
100
100
20
20
N.A.
13.3
N.A.
N.A.
93.3
100
73.3
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
50
10
0
0
10
0
0
0
0
0
10
0
50
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
50
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
10
10
20
0
0
0
0
0
10
10
20
0
0
0
% F
% Gly:
10
0
0
0
10
0
20
0
10
0
10
0
20
10
10
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
50
0
0
20
10
10
10
0
0
0
0
10
% K
% Leu:
0
0
0
0
0
10
0
0
0
0
0
10
0
0
0
% L
% Met:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% N
% Pro:
10
0
0
10
20
40
10
0
10
10
60
0
30
10
10
% P
% Gln:
0
0
0
0
0
0
0
0
30
0
0
0
40
0
0
% Q
% Arg:
0
0
50
0
0
0
0
0
10
0
0
0
0
0
0
% R
% Ser:
0
20
10
10
10
20
0
30
0
0
10
40
0
10
50
% S
% Thr:
0
0
0
0
50
10
0
50
20
60
10
20
0
0
0
% T
% Val:
0
20
0
0
0
0
50
0
10
0
0
0
10
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
10
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _