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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SMG7 All Species: 19.39
Human Site: T637 Identified Species: 47.41
UniProt: Q92540 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92540 NP_775179.1 1137 127282 T637 R K T P V T Q T P T Q A S N S
Chimpanzee Pan troglodytes XP_514048 1195 133575 T645 R K T P V T Q T P T Q A S N S
Rhesus Macaque Macaca mulatta XP_001109289 1447 160801 Y906 A F S M G S G Y T F P A G V S
Dog Lupus familis XP_537157 1072 119777 P598 F P P L P S R P G F P P P T Y
Cat Felis silvestris
Mouse Mus musculus Q5RJH6 1138 126823 F636 S M G S G Y T F P A G V S V P
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516046 1166 130499 T664 R K T P V T P T P S Q A N S S
Chicken Gallus gallus XP_422287 1122 125325 T620 R K T P V T Q T P S Q A S S S
Frog Xenopus laevis NP_001086379 1129 126148 T632 R K T A V T T T S S P S S N T
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393064 1132 126772 T641 I S P T K S V T P S G N K N I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_197441 1059 116987 K585 Y F D S K K K K F L V G V K P
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.5 73.2 91.8 N.A. 91.6 N.A. N.A. 89.1 88.7 71.9 N.A. N.A. N.A. 28.3 N.A. N.A.
Protein Similarity: 100 94.9 73.8 93.4 N.A. 93.7 N.A. N.A. 92.5 93.2 82.6 N.A. N.A. N.A. 45.7 N.A. N.A.
P-Site Identity: 100 100 13.3 0 N.A. 13.3 N.A. N.A. 73.3 86.6 53.3 N.A. N.A. N.A. 20 N.A. N.A.
P-Site Similarity: 100 100 26.6 13.3 N.A. 13.3 N.A. N.A. 93.3 100 73.3 N.A. N.A. N.A. 33.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 21.1 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 36.8 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 10 0 0 0 0 0 10 0 50 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 10 20 0 0 0 0 0 10 10 20 0 0 0 0 0 % F
% Gly: 0 0 10 0 20 0 10 0 10 0 20 10 10 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % I
% Lys: 0 50 0 0 20 10 10 10 0 0 0 0 10 10 0 % K
% Leu: 0 0 0 10 0 0 0 0 0 10 0 0 0 0 0 % L
% Met: 0 10 0 10 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 10 10 40 0 % N
% Pro: 0 10 20 40 10 0 10 10 60 0 30 10 10 0 20 % P
% Gln: 0 0 0 0 0 0 30 0 0 0 40 0 0 0 0 % Q
% Arg: 50 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % R
% Ser: 10 10 10 20 0 30 0 0 10 40 0 10 50 20 50 % S
% Thr: 0 0 50 10 0 50 20 60 10 20 0 0 0 10 10 % T
% Val: 0 0 0 0 50 0 10 0 0 0 10 10 10 20 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 0 10 0 10 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _