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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TM9SF4
All Species:
23.94
Human Site:
Y340
Identified Species:
40.51
UniProt:
Q92544
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92544
NP_055557.2
642
74519
Y340
D
V
F
R
P
P
Q
Y
P
M
I
L
S
S
L
Chimpanzee
Pan troglodytes
XP_001154785
625
72523
S333
I
L
S
S
L
L
G
S
G
I
Q
L
F
C
M
Rhesus Macaque
Macaca mulatta
XP_001108787
643
74626
Q340
G
D
V
F
R
P
P
Q
Y
P
M
I
L
S
S
Dog
Lupus familis
XP_534381
642
74477
Y340
D
V
F
R
P
P
Q
Y
P
M
I
L
S
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BH24
643
74675
Y341
D
V
F
R
P
P
Q
Y
P
M
I
L
S
S
L
Rat
Rattus norvegicus
Q4KLL4
643
74657
Y341
D
V
F
R
P
P
Q
Y
P
M
I
L
S
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417455
668
77283
Y366
D
V
F
R
P
P
Q
Y
P
M
I
L
S
S
L
Frog
Xenopus laevis
NP_001083319
642
74183
Y340
D
V
F
R
P
P
Q
Y
P
M
I
L
S
S
L
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609669
630
72518
F332
P
P
K
N
T
R
L
F
S
A
I
I
G
S
G
Honey Bee
Apis mellifera
XP_625101
632
72392
N330
D
V
F
R
P
P
P
N
P
R
L
F
A
A
V
Nematode Worm
Caenorhab. elegans
NP_492451
619
69789
I337
Q
L
L
G
M
S
A
I
V
V
V
C
A
M
L
Sea Urchin
Strong. purpuratus
XP_792009
713
80849
K412
V
F
R
P
P
R
Y
K
Q
L
L
A
A
L
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_187991
641
74215
N339
D
V
F
R
P
P
V
N
S
G
L
L
C
V
Y
Baker's Yeast
Sacchar. cerevisiae
P32802
667
75944
Q365
D
V
F
R
S
P
S
Q
S
L
T
L
S
I
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.3
99.6
98.5
N.A.
96.7
96.7
N.A.
N.A.
88.7
88.9
N.A.
N.A.
63.2
60.7
55.4
49.9
Protein Similarity:
100
97.3
99.6
99.2
N.A.
97.3
97.1
N.A.
N.A.
92.2
94.2
N.A.
N.A.
78.8
77.4
73.3
66.2
P-Site Identity:
100
6.6
13.3
100
N.A.
100
100
N.A.
N.A.
100
100
N.A.
N.A.
13.3
46.6
6.6
6.6
P-Site Similarity:
100
26.6
26.6
100
N.A.
100
100
N.A.
N.A.
100
100
N.A.
N.A.
26.6
73.3
33.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
49.3
36.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
70.5
56.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
46.6
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
0
0
8
0
8
22
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
8
8
0
% C
% Asp:
65
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
8
65
8
0
0
0
8
0
0
0
8
8
0
0
% F
% Gly:
8
0
0
8
0
0
8
0
8
8
0
0
8
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
8
0
8
50
15
0
8
0
% I
% Lys:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% K
% Leu:
0
15
8
0
8
8
8
0
0
15
22
65
8
8
58
% L
% Met:
0
0
0
0
8
0
0
0
0
43
8
0
0
8
8
% M
% Asn:
0
0
0
8
0
0
0
15
0
0
0
0
0
0
0
% N
% Pro:
8
8
0
8
65
72
15
0
50
8
0
0
0
0
0
% P
% Gln:
8
0
0
0
0
0
43
15
8
0
8
0
0
0
0
% Q
% Arg:
0
0
8
65
8
15
0
0
0
8
0
0
0
0
0
% R
% Ser:
0
0
8
8
8
8
8
8
22
0
0
0
50
58
8
% S
% Thr:
0
0
0
0
8
0
0
0
0
0
8
0
0
0
0
% T
% Val:
8
65
8
0
0
0
8
0
8
8
8
0
0
8
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
43
8
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _