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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TM9SF4
All Species:
40.3
Human Site:
Y401
Identified Species:
68.21
UniProt:
Q92544
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92544
NP_055557.2
642
74519
Y401
G
F
S
A
G
R
L
Y
R
T
L
K
G
H
R
Chimpanzee
Pan troglodytes
XP_001154785
625
72523
K388
G
R
L
Y
R
T
L
K
G
H
R
W
K
K
G
Rhesus Macaque
Macaca mulatta
XP_001108787
643
74626
Y402
G
F
S
A
G
R
L
Y
R
T
L
K
G
H
R
Dog
Lupus familis
XP_534381
642
74477
Y401
G
F
S
A
G
R
L
Y
R
T
L
K
G
H
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BH24
643
74675
Y402
G
F
S
A
G
R
L
Y
R
T
L
K
G
H
R
Rat
Rattus norvegicus
Q4KLL4
643
74657
Y402
G
F
S
A
G
R
L
Y
R
T
L
K
G
H
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417455
668
77283
Y427
G
F
F
A
G
R
L
Y
R
T
L
K
G
H
R
Frog
Xenopus laevis
NP_001083319
642
74183
Y401
G
F
F
A
G
R
L
Y
R
T
L
K
G
H
R
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609669
630
72518
Y389
G
Y
Y
A
A
R
L
Y
K
T
M
K
G
R
E
Honey Bee
Apis mellifera
XP_625101
632
72392
Y391
G
Y
F
S
A
R
L
Y
K
T
M
R
G
R
K
Nematode Worm
Caenorhab. elegans
NP_492451
619
69789
T393
P
I
R
C
A
V
Q
T
A
T
L
F
P
S
L
Sea Urchin
Strong. purpuratus
XP_792009
713
80849
Y472
G
Y
F
S
G
R
L
Y
K
T
M
K
G
T
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_187991
641
74215
H400
G
Y
S
S
S
R
L
H
K
M
F
K
G
N
K
Baker's Yeast
Sacchar. cerevisiae
P32802
667
75944
Y426
S
Y
T
S
M
G
I
Y
K
F
F
N
G
P
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.3
99.6
98.5
N.A.
96.7
96.7
N.A.
N.A.
88.7
88.9
N.A.
N.A.
63.2
60.7
55.4
49.9
Protein Similarity:
100
97.3
99.6
99.2
N.A.
97.3
97.1
N.A.
N.A.
92.2
94.2
N.A.
N.A.
78.8
77.4
73.3
66.2
P-Site Identity:
100
13.3
100
100
N.A.
100
100
N.A.
N.A.
93.3
93.3
N.A.
N.A.
53.3
40
13.3
60
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
N.A.
93.3
93.3
N.A.
N.A.
73.3
80
13.3
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
49.3
36.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
70.5
56.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
80
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
58
22
0
0
0
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% E
% Phe:
0
50
29
0
0
0
0
0
0
8
15
8
0
0
0
% F
% Gly:
86
0
0
0
58
8
0
0
8
0
0
0
86
0
8
% G
% His:
0
0
0
0
0
0
0
8
0
8
0
0
0
50
0
% H
% Ile:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
8
36
0
0
72
8
8
15
% K
% Leu:
0
0
8
0
0
0
86
0
0
0
58
0
0
0
8
% L
% Met:
0
0
0
0
8
0
0
0
0
8
22
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% N
% Pro:
8
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% P
% Gln:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
8
0
8
79
0
0
50
0
8
8
0
15
58
% R
% Ser:
8
0
43
29
8
0
0
0
0
0
0
0
0
8
0
% S
% Thr:
0
0
8
0
0
8
0
8
0
79
0
0
0
8
0
% T
% Val:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
36
8
8
0
0
0
79
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _