KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TM9SF4
All Species:
26.67
Human Site:
Y71
Identified Species:
45.13
UniProt:
Q92544
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92544
NP_055557.2
642
74519
Y71
C
Q
P
S
K
I
T
Y
K
A
E
N
L
G
E
Chimpanzee
Pan troglodytes
XP_001154785
625
72523
D66
L
G
E
V
L
R
G
D
R
I
V
N
T
P
F
Rhesus Macaque
Macaca mulatta
XP_001108787
643
74626
Y71
C
Q
P
S
K
I
T
Y
K
A
E
N
L
G
E
Dog
Lupus familis
XP_534381
642
74477
Y71
C
Q
P
S
K
I
T
Y
K
A
E
N
L
G
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BH24
643
74675
Y71
C
Q
P
I
K
I
T
Y
K
A
E
N
L
G
E
Rat
Rattus norvegicus
Q4KLL4
643
74657
Y71
C
Q
P
N
K
I
T
Y
K
A
E
N
L
G
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417455
668
77283
Y97
C
Q
P
T
E
I
T
Y
K
A
E
N
L
G
E
Frog
Xenopus laevis
NP_001083319
642
74183
Y71
C
Q
P
P
E
I
T
Y
K
S
E
N
L
G
E
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609669
630
72518
F65
Y
Q
Y
Y
S
L
R
F
C
Y
P
K
N
G
T
Honey Bee
Apis mellifera
XP_625101
632
72392
C63
D
Y
Y
S
I
P
F
C
V
P
K
N
G
S
K
Nematode Worm
Caenorhab. elegans
NP_492451
619
69789
I69
C
K
P
A
N
G
D
I
Q
Y
K
S
E
N
L
Sea Urchin
Strong. purpuratus
XP_792009
713
80849
P145
Y
S
V
K
L
C
P
P
V
A
G
N
I
V
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_187991
641
74215
K72
L
N
Y
C
K
P
P
K
I
L
N
N
A
E
N
Baker's Yeast
Sacchar. cerevisiae
P32802
667
75944
K90
C
Q
P
E
K
V
E
K
Q
P
E
S
L
G
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.3
99.6
98.5
N.A.
96.7
96.7
N.A.
N.A.
88.7
88.9
N.A.
N.A.
63.2
60.7
55.4
49.9
Protein Similarity:
100
97.3
99.6
99.2
N.A.
97.3
97.1
N.A.
N.A.
92.2
94.2
N.A.
N.A.
78.8
77.4
73.3
66.2
P-Site Identity:
100
6.6
100
100
N.A.
93.3
93.3
N.A.
N.A.
86.6
80
N.A.
N.A.
13.3
13.3
13.3
13.3
P-Site Similarity:
100
13.3
100
100
N.A.
93.3
100
N.A.
N.A.
100
93.3
N.A.
N.A.
26.6
26.6
46.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
49.3
36.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
70.5
56.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
0
0
50
0
0
8
0
0
% A
% Cys:
65
0
0
8
0
8
0
8
8
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% D
% Glu:
0
0
8
8
15
0
8
0
0
0
58
0
8
8
50
% E
% Phe:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
8
% F
% Gly:
0
8
0
0
0
8
8
0
0
0
8
0
8
65
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
8
8
50
0
8
8
8
0
0
8
0
0
% I
% Lys:
0
8
0
8
50
0
0
15
50
0
15
8
0
0
8
% K
% Leu:
15
0
0
0
15
8
0
0
0
8
0
0
58
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
8
8
0
0
0
0
0
8
79
8
8
8
% N
% Pro:
0
0
65
8
0
15
15
8
0
15
8
0
0
8
0
% P
% Gln:
0
65
0
0
0
0
0
0
15
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
8
8
0
8
0
0
0
0
0
0
% R
% Ser:
0
8
0
29
8
0
0
0
0
8
0
15
0
8
8
% S
% Thr:
0
0
0
8
0
0
50
0
0
0
0
0
8
0
8
% T
% Val:
0
0
8
8
0
8
0
0
15
0
8
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
15
8
22
8
0
0
0
50
0
15
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _