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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMEM131 All Species: 13.64
Human Site: S1174 Identified Species: 30
UniProt: Q92545 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92545 NP_056163.1 1834 200810 S1174 P S V H P H S S H S N R N S A
Chimpanzee Pan troglodytes XP_515638 1883 205095 S1223 P S V H P H S S H S N R N S A
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_531794 1765 193338 S1138 S S R T S A Q S A S K A S P L
Cat Felis silvestris
Mouse Mus musculus O70472 1829 200481 S1171 T S V H P H S S H G S K N S A
Rat Rattus norvegicus XP_237056 1873 204160 S1218 T S V H P H S S H G S K N S A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514076 1953 212261 H1173 C N P A T H P H G G R S S A E
Chicken Gallus gallus XP_001233589 1923 210583 H1253 C S A T A H L H S N R N A P D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001923340 1799 197701 N1159 V R I Q S D P N L N D F A D S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V7H4 1567 173302 V942 S G N E A V V V T R S F T A R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_498059 1831 205776 M1171 R P P F E N I M Y Y S C V T A
Sea Urchin Strong. purpuratus XP_795113 1144 126924 M519 E R I D D S N M D G N E D T V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97 N.A. 91.8 N.A. 89.6 87.8 N.A. 69.6 76.1 N.A. 61.1 N.A. 24.3 N.A. 24.9 23.1
Protein Similarity: 100 97.1 N.A. 93.8 N.A. 94.2 92.4 N.A. 78.5 84 N.A. 74.5 N.A. 41.3 N.A. 43.8 35.7
P-Site Identity: 100 100 N.A. 20 N.A. 73.3 73.3 N.A. 6.6 13.3 N.A. 0 N.A. 0 N.A. 6.6 6.6
P-Site Similarity: 100 100 N.A. 26.6 N.A. 86.6 86.6 N.A. 26.6 20 N.A. 33.3 N.A. 13.3 N.A. 33.3 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 10 19 10 0 0 10 0 0 10 19 19 46 % A
% Cys: 19 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % C
% Asp: 0 0 0 10 10 10 0 0 10 0 10 0 10 10 10 % D
% Glu: 10 0 0 10 10 0 0 0 0 0 0 10 0 0 10 % E
% Phe: 0 0 0 10 0 0 0 0 0 0 0 19 0 0 0 % F
% Gly: 0 10 0 0 0 0 0 0 10 37 0 0 0 0 0 % G
% His: 0 0 0 37 0 55 0 19 37 0 0 0 0 0 0 % H
% Ile: 0 0 19 0 0 0 10 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 10 19 0 0 0 % K
% Leu: 0 0 0 0 0 0 10 0 10 0 0 0 0 0 10 % L
% Met: 0 0 0 0 0 0 0 19 0 0 0 0 0 0 0 % M
% Asn: 0 10 10 0 0 10 10 10 0 19 28 10 37 0 0 % N
% Pro: 19 10 19 0 37 0 19 0 0 0 0 0 0 19 0 % P
% Gln: 0 0 0 10 0 0 10 0 0 0 0 0 0 0 0 % Q
% Arg: 10 19 10 0 0 0 0 0 0 10 19 19 0 0 10 % R
% Ser: 19 55 0 0 19 10 37 46 10 28 37 10 19 37 10 % S
% Thr: 19 0 0 19 10 0 0 0 10 0 0 0 10 19 0 % T
% Val: 10 0 37 0 0 10 10 10 0 0 0 0 10 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 10 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _