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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMEM131 All Species: 14.55
Human Site: S1435 Identified Species: 32
UniProt: Q92545 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92545 NP_056163.1 1834 200810 S1435 P T D V K P S S L E L P Y T P
Chimpanzee Pan troglodytes XP_515638 1883 205095 S1484 P T D V K P S S L E L P Y T P
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_531794 1765 193338 L1367 T D V K P S S L E L P Y T P P
Cat Felis silvestris
Mouse Mus musculus O70472 1829 200481 D1428 A K K E I P T D V K G S S F E
Rat Rattus norvegicus XP_237056 1873 204160 G1477 I P T D V K G G S F E L P Y T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514076 1953 212261 S1426 P G D I K S S S L E L P Y T P
Chicken Gallus gallus XP_001233589 1923 210583 S1514 P V D V K T S S L E L P Y T P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001923340 1799 197701 E1392 V A I D N G K E R E E I T P S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V7H4 1567 173302 T1171 K P K T V V S T P V T P P A A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_498059 1831 205776 T1417 M E P A K K T T P G P S P K P
Sea Urchin Strong. purpuratus XP_795113 1144 126924 K748 L A D R Q E A K F P L T Y I G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97 N.A. 91.8 N.A. 89.6 87.8 N.A. 69.6 76.1 N.A. 61.1 N.A. 24.3 N.A. 24.9 23.1
Protein Similarity: 100 97.1 N.A. 93.8 N.A. 94.2 92.4 N.A. 78.5 84 N.A. 74.5 N.A. 41.3 N.A. 43.8 35.7
P-Site Identity: 100 100 N.A. 13.3 N.A. 6.6 0 N.A. 80 86.6 N.A. 6.6 N.A. 13.3 N.A. 13.3 20
P-Site Similarity: 100 100 N.A. 13.3 N.A. 26.6 0 N.A. 86.6 86.6 N.A. 6.6 N.A. 20 N.A. 26.6 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 19 0 10 0 0 10 0 0 0 0 0 0 10 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 46 19 0 0 0 10 0 0 0 0 0 0 0 % D
% Glu: 0 10 0 10 0 10 0 10 10 46 19 0 0 0 10 % E
% Phe: 0 0 0 0 0 0 0 0 10 10 0 0 0 10 0 % F
% Gly: 0 10 0 0 0 10 10 10 0 10 10 0 0 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 10 10 10 0 0 0 0 0 0 10 0 10 0 % I
% Lys: 10 10 19 10 46 19 10 10 0 10 0 0 0 10 0 % K
% Leu: 10 0 0 0 0 0 0 10 37 10 46 10 0 0 0 % L
% Met: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 37 19 10 0 10 28 0 0 19 10 19 46 28 19 55 % P
% Gln: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 10 0 0 0 0 10 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 19 55 37 10 0 0 19 10 0 10 % S
% Thr: 10 19 10 10 0 10 19 19 0 0 10 10 19 37 10 % T
% Val: 10 10 10 28 19 10 0 0 10 10 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 10 46 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _