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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM131
All Species:
19.7
Human Site:
S661
Identified Species:
43.33
UniProt:
Q92545
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92545
NP_056163.1
1834
200810
S661
V
K
I
Q
Q
I
R
S
L
S
E
D
V
R
F
Chimpanzee
Pan troglodytes
XP_515638
1883
205095
S710
V
K
I
Q
Q
I
R
S
L
S
E
D
V
R
F
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_531794
1765
193338
Y640
L
Q
C
G
D
H
C
Y
V
G
L
P
F
L
S
Cat
Felis silvestris
Mouse
Mus musculus
O70472
1829
200481
S660
V
K
I
Q
Q
I
R
S
L
S
E
D
V
R
F
Rat
Rattus norvegicus
XP_237056
1873
204160
S707
V
K
I
Q
Q
I
R
S
L
S
E
D
V
R
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514076
1953
212261
V665
I
R
S
L
S
D
D
V
R
F
Y
H
K
Q
L
Chicken
Gallus gallus
XP_001233589
1923
210583
S740
V
K
I
Q
H
I
R
S
L
S
E
D
V
R
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001923340
1799
197701
S649
L
I
A
V
G
T
L
S
C
S
P
K
H
I
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V7H4
1567
173302
L444
E
S
V
E
L
L
R
L
N
L
L
N
D
Q
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_498059
1831
205776
L662
G
K
I
F
D
L
E
L
K
V
P
S
D
G
V
Sea Urchin
Strong. purpuratus
XP_795113
1144
126924
L21
I
Q
M
W
F
T
L
L
L
G
V
L
Q
V
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97
N.A.
91.8
N.A.
89.6
87.8
N.A.
69.6
76.1
N.A.
61.1
N.A.
24.3
N.A.
24.9
23.1
Protein Similarity:
100
97.1
N.A.
93.8
N.A.
94.2
92.4
N.A.
78.5
84
N.A.
74.5
N.A.
41.3
N.A.
43.8
35.7
P-Site Identity:
100
100
N.A.
0
N.A.
100
100
N.A.
0
93.3
N.A.
13.3
N.A.
6.6
N.A.
13.3
6.6
P-Site Similarity:
100
100
N.A.
20
N.A.
100
100
N.A.
20
93.3
N.A.
20
N.A.
40
N.A.
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
10
0
0
0
10
0
10
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
19
10
10
0
0
0
0
46
19
0
0
% D
% Glu:
10
0
0
10
0
0
10
0
0
0
46
0
0
0
0
% E
% Phe:
0
0
0
10
10
0
0
0
0
10
0
0
10
0
46
% F
% Gly:
10
0
0
10
10
0
0
0
0
19
0
0
0
10
0
% G
% His:
0
0
0
0
10
10
0
0
0
0
0
10
10
0
0
% H
% Ile:
19
10
55
0
0
46
0
0
0
0
0
0
0
10
19
% I
% Lys:
0
55
0
0
0
0
0
0
10
0
0
10
10
0
0
% K
% Leu:
19
0
0
10
10
19
19
28
55
10
19
10
0
10
10
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
0
0
10
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
19
10
0
0
0
% P
% Gln:
0
19
0
46
37
0
0
0
0
0
0
0
10
19
0
% Q
% Arg:
0
10
0
0
0
0
55
0
10
0
0
0
0
46
0
% R
% Ser:
0
10
10
0
10
0
0
55
0
55
0
10
0
0
10
% S
% Thr:
0
0
0
0
0
19
0
0
0
0
0
0
0
0
0
% T
% Val:
46
0
10
10
0
0
0
10
10
10
10
0
46
10
19
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _