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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMEM131 All Species: 20.3
Human Site: S782 Identified Species: 44.67
UniProt: Q92545 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92545 NP_056163.1 1834 200810 S782 L S W P S I L S S P R H L K F
Chimpanzee Pan troglodytes XP_515638 1883 205095 S831 L S W P S I L S S P R H L K F
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_531794 1765 193338 Q751 A D V P V Y I Q F I P L A L Y
Cat Felis silvestris
Mouse Mus musculus O70472 1829 200481 S781 L S W P S V L S S P R L L K F
Rat Rattus norvegicus XP_237056 1873 204160 S828 L S W P S V L S S P R L V R F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514076 1953 212261 S781 L L W P S L L S S P R L L N F
Chicken Gallus gallus XP_001233589 1923 210583 S861 M V W P S I L S S P R Q L S F
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001923340 1799 197701 R766 L H Q R L L K R W R E L K E Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V7H4 1567 173302 I555 L G C R A T A I G H P V S V E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_498059 1831 205776 C775 M F S P S A P C E H D Y C Y L
Sea Urchin Strong. purpuratus XP_795113 1144 126924 F132 I S G T T P H F H C S F F Q E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97 N.A. 91.8 N.A. 89.6 87.8 N.A. 69.6 76.1 N.A. 61.1 N.A. 24.3 N.A. 24.9 23.1
Protein Similarity: 100 97.1 N.A. 93.8 N.A. 94.2 92.4 N.A. 78.5 84 N.A. 74.5 N.A. 41.3 N.A. 43.8 35.7
P-Site Identity: 100 100 N.A. 6.6 N.A. 86.6 73.3 N.A. 73.3 73.3 N.A. 6.6 N.A. 6.6 N.A. 13.3 6.6
P-Site Similarity: 100 100 N.A. 20 N.A. 93.3 93.3 N.A. 80 80 N.A. 20 N.A. 13.3 N.A. 26.6 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 10 10 10 0 0 0 0 0 10 0 0 % A
% Cys: 0 0 10 0 0 0 0 10 0 10 0 0 10 0 0 % C
% Asp: 0 10 0 0 0 0 0 0 0 0 10 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 10 0 10 0 0 10 19 % E
% Phe: 0 10 0 0 0 0 0 10 10 0 0 10 10 0 55 % F
% Gly: 0 10 10 0 0 0 0 0 10 0 0 0 0 0 0 % G
% His: 0 10 0 0 0 0 10 0 10 19 0 19 0 0 0 % H
% Ile: 10 0 0 0 0 28 10 10 0 10 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 10 0 0 0 0 0 10 28 0 % K
% Leu: 64 10 0 0 10 19 55 0 0 0 0 46 46 10 10 % L
% Met: 19 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % N
% Pro: 0 0 0 73 0 10 10 0 0 55 19 0 0 0 0 % P
% Gln: 0 0 10 0 0 0 0 10 0 0 0 10 0 10 10 % Q
% Arg: 0 0 0 19 0 0 0 10 0 10 55 0 0 10 0 % R
% Ser: 0 46 10 0 64 0 0 55 55 0 10 0 10 10 0 % S
% Thr: 0 0 0 10 10 10 0 0 0 0 0 0 0 0 0 % T
% Val: 0 10 10 0 10 19 0 0 0 0 0 10 10 10 0 % V
% Trp: 0 0 55 0 0 0 0 0 10 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 10 0 0 0 0 0 10 0 10 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _