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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MRPS27
All Species:
17.27
Human Site:
T374
Identified Species:
47.5
UniProt:
Q92552
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92552
NP_055899.2
414
47611
T374
C
E
A
E
D
I
A
T
Y
E
Q
N
L
Q
Q
Chimpanzee
Pan troglodytes
XP_517715
414
47651
T374
C
E
A
E
D
I
A
T
Y
E
Q
N
L
Q
Q
Rhesus Macaque
Macaca mulatta
XP_001098829
414
47944
T374
C
E
A
E
D
I
V
T
Y
E
Q
N
L
Q
Q
Dog
Lupus familis
XP_852973
452
51511
T375
C
E
A
E
D
M
A
T
Y
E
Q
K
L
Q
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8BK72
415
47776
T375
C
E
A
E
D
L
A
T
Y
E
Q
K
L
R
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512710
457
52310
R413
C
E
A
E
D
V
A
R
Y
E
Q
K
L
Q
E
Chicken
Gallus gallus
XP_424803
407
46722
K367
C
E
V
E
D
I
A
K
H
E
Q
K
L
K
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001003778
398
45789
E372
R
M
Q
D
W
G
D
E
Q
Q
K
L
I
Q
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_799111
372
42538
G347
E
L
L
R
A
T
G
G
I
K
Y
W
A
E
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
94.1
75.4
N.A.
76.3
N.A.
N.A.
58.8
64.4
N.A.
50.4
N.A.
N.A.
N.A.
N.A.
28.7
Protein Similarity:
100
99.7
96.1
82.9
N.A.
86.7
N.A.
N.A.
74.4
81.1
N.A.
69.5
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Identity:
100
100
93.3
86.6
N.A.
73.3
N.A.
N.A.
73.3
60
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
93.3
93.3
N.A.
93.3
N.A.
N.A.
86.6
80
N.A.
40
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
67
0
12
0
67
0
0
0
0
0
12
0
0
% A
% Cys:
78
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
12
78
0
12
0
0
0
0
0
0
0
0
% D
% Glu:
12
78
0
78
0
0
0
12
0
78
0
0
0
12
34
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
12
12
12
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
45
0
0
12
0
0
0
12
0
0
% I
% Lys:
0
0
0
0
0
0
0
12
0
12
12
45
0
12
12
% K
% Leu:
0
12
12
0
0
12
0
0
0
0
0
12
78
0
0
% L
% Met:
0
12
0
0
0
12
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
34
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
12
0
0
0
0
0
12
12
78
0
0
67
45
% Q
% Arg:
12
0
0
12
0
0
0
12
0
0
0
0
0
12
12
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
12
0
56
0
0
0
0
0
0
0
% T
% Val:
0
0
12
0
0
12
12
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
12
0
0
0
0
0
0
12
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
67
0
12
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _