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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP3S1
All Species:
26.97
Human Site:
S59
Identified Species:
42.38
UniProt:
Q92572
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92572
NP_001275.1
193
21732
S59
G
G
L
L
I
G
G
S
D
N
K
L
I
Y
R
Chimpanzee
Pan troglodytes
XP_001148407
293
32121
S159
G
G
L
L
I
G
G
S
D
N
K
L
I
Y
R
Rhesus Macaque
Macaca mulatta
XP_001094426
205
23394
S59
G
G
S
L
I
G
G
S
D
Y
K
L
I
Y
R
Dog
Lupus familis
XP_849444
169
18875
I56
F
L
E
G
G
L
L
I
G
G
S
D
N
K
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9DB50
160
18911
R52
M
C
S
F
L
E
W
R
D
L
K
I
V
Y
K
Rat
Rattus norvegicus
P62744
142
16999
V35
K
Q
K
L
I
E
E
V
H
A
V
V
T
V
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505884
170
18952
S56
Y
F
V
F
C
V
D
S
S
E
S
E
L
G
I
Chicken
Gallus gallus
NP_001006586
193
21787
S59
G
G
L
L
I
G
G
S
D
N
K
L
I
Y
R
Frog
Xenopus laevis
NP_001080137
193
21761
S59
G
G
L
L
I
G
G
S
D
N
K
L
I
Y
R
Zebra Danio
Brachydanio rerio
NP_001005964
193
21742
S59
G
G
L
L
I
G
G
S
D
N
K
L
I
Y
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397320
191
21930
S59
G
G
S
L
I
G
G
S
D
Y
K
L
I
Y
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O50016
132
15996
E24
A
K
Y
Y
V
P
L
E
D
S
E
K
H
K
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8H1F4
181
19858
E65
E
A
E
I
T
L
L
E
S
N
I
V
V
Y
K
Baker's Yeast
Sacchar. cerevisiae
P47064
194
21919
E71
N
N
D
E
V
N
N
E
D
I
Q
I
I
Y
K
Red Bread Mold
Neurospora crassa
Q7SAQ1
143
16937
I35
K
I
K
L
K
G
E
I
H
R
L
V
A
P
R
Conservation
Percent
Protein Identity:
100
65.8
79
87.5
N.A.
34.2
33.6
N.A.
88
98.9
97.4
92.7
N.A.
N.A.
78.2
N.A.
N.A.
Protein Similarity:
100
65.8
86.8
87.5
N.A.
54.4
50.2
N.A.
88
99.4
98.4
98.9
N.A.
N.A.
88
N.A.
N.A.
P-Site Identity:
100
100
86.6
0
N.A.
20
20
N.A.
6.6
100
100
100
N.A.
N.A.
86.6
N.A.
N.A.
P-Site Similarity:
100
100
86.6
0
N.A.
46.6
26.6
N.A.
20
100
100
100
N.A.
N.A.
86.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
31.6
N.A.
21.2
38.6
33.1
Protein Similarity:
N.A.
44.5
N.A.
38.3
59.2
50.2
P-Site Identity:
N.A.
6.6
N.A.
13.3
20
20
P-Site Similarity:
N.A.
26.6
N.A.
40
46.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
0
0
0
0
0
0
7
0
0
7
0
0
% A
% Cys:
0
7
0
0
7
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
0
0
0
7
0
67
0
0
7
0
0
0
% D
% Glu:
7
0
14
7
0
14
14
20
0
7
7
7
0
0
0
% E
% Phe:
7
7
0
14
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
47
47
0
7
7
54
47
0
7
7
0
0
0
7
0
% G
% His:
0
0
0
0
0
0
0
0
14
0
0
0
7
0
0
% H
% Ile:
0
7
0
7
54
0
0
14
0
7
7
14
54
0
7
% I
% Lys:
14
7
14
0
7
0
0
0
0
0
54
7
0
14
20
% K
% Leu:
0
7
34
60
7
14
20
0
0
7
7
47
7
0
7
% L
% Met:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
7
0
0
0
7
7
0
0
40
0
0
7
0
0
% N
% Pro:
0
0
0
0
0
7
0
0
0
0
0
0
0
7
0
% P
% Gln:
0
7
0
0
0
0
0
0
0
0
7
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
7
0
7
0
0
0
0
60
% R
% Ser:
0
0
20
0
0
0
0
54
14
7
14
0
0
0
0
% S
% Thr:
0
0
0
0
7
0
0
0
0
0
0
0
7
0
0
% T
% Val:
0
0
7
0
14
7
0
7
0
0
7
20
14
7
7
% V
% Trp:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
7
7
0
0
0
0
0
14
0
0
0
67
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _