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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC9A6 All Species: 19.09
Human Site: T378 Identified Species: 38.18
UniProt: Q92581 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92581 NP_001036002.1 669 74162 T378 S T E S Q H R T K Q L F E L L
Chimpanzee Pan troglodytes XP_529172 631 70128 G356 A F V A I F L G R A A N I Y P
Rhesus Macaque Macaca mulatta XP_001101621 669 74087 T378 S T E S Q H R T K Q L F E L L
Dog Lupus familis XP_538181 658 72539 T367 S T E S Q H R T K Q L F E L L
Cat Felis silvestris
Mouse Mus musculus Q8BLV3 726 80271 S410 S V E S R S R S K Q L F E V L
Rat Rattus norvegicus Q4L208 575 64590 Y304 I I F A Y L P Y G L A E G I S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514332 464 51149 S193 D A V A I V L S S S I V A Y Q
Chicken Gallus gallus Q5ZJ75 574 64115 Y303 I I F A Y L P Y G L A E G I S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001091726 697 77397 T398 S P E S Q D R T K Q L F E L L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O16452 670 75527 G368 C L I Y R A I G I I V Q C F I
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RWU6 535 59320 F263 Q N L E C C L F V L F P Y F S
Baker's Yeast Sacchar. cerevisiae Q04121 633 70130 I360 L S E N F I F I Y L G L E L F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 82.2 99.4 81.1 N.A. 64.7 29.1 N.A. 60.5 29.7 N.A. 73.8 N.A. N.A. N.A. 25.2 N.A.
Protein Similarity: 100 84.7 99.5 84.7 N.A. 74.3 46.3 N.A. 64.2 47.6 N.A. 81.7 N.A. N.A. N.A. 46.7 N.A.
P-Site Identity: 100 0 100 100 N.A. 66.6 0 N.A. 0 0 N.A. 86.6 N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 100 20 100 100 N.A. 86.6 13.3 N.A. 20 13.3 N.A. 86.6 N.A. N.A. N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 30.6 27 N.A.
Protein Similarity: N.A. N.A. N.A. 46.6 46.7 N.A.
P-Site Identity: N.A. N.A. N.A. 0 20 N.A.
P-Site Similarity: N.A. N.A. N.A. 0 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 0 34 0 9 0 0 0 9 25 0 9 0 0 % A
% Cys: 9 0 0 0 9 9 0 0 0 0 0 0 9 0 0 % C
% Asp: 9 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 50 9 0 0 0 0 0 0 0 17 50 0 0 % E
% Phe: 0 9 17 0 9 9 9 9 0 0 9 42 0 17 9 % F
% Gly: 0 0 0 0 0 0 0 17 17 0 9 0 17 0 0 % G
% His: 0 0 0 0 0 25 0 0 0 0 0 0 0 0 0 % H
% Ile: 17 17 9 0 17 9 9 9 9 9 9 0 9 17 9 % I
% Lys: 0 0 0 0 0 0 0 0 42 0 0 0 0 0 0 % K
% Leu: 9 9 9 0 0 17 25 0 0 34 42 9 0 42 42 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 9 0 9 0 0 0 0 0 0 0 9 0 0 0 % N
% Pro: 0 9 0 0 0 0 17 0 0 0 0 9 0 0 9 % P
% Gln: 9 0 0 0 34 0 0 0 0 42 0 9 0 0 9 % Q
% Arg: 0 0 0 0 17 0 42 0 9 0 0 0 0 0 0 % R
% Ser: 42 9 0 42 0 9 0 17 9 9 0 0 0 0 25 % S
% Thr: 0 25 0 0 0 0 0 34 0 0 0 0 0 0 0 % T
% Val: 0 9 17 0 0 9 0 0 9 0 9 9 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 9 17 0 0 17 9 0 0 0 9 17 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _