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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NDRG1
All Species:
18.48
Human Site:
S317
Identified Species:
45.19
UniProt:
Q92597
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92597
NP_001128714.1
394
42835
S317
Q
G
M
G
Y
M
P
S
A
S
M
T
R
L
M
Chimpanzee
Pan troglodytes
A5A6K6
357
39342
P281
M
A
D
S
G
G
Q
P
Q
L
T
Q
P
G
K
Rhesus Macaque
Macaca mulatta
XP_001088529
394
42883
S317
Q
G
M
G
Y
M
P
S
A
S
M
T
R
L
M
Dog
Lupus familis
XP_539170
384
41718
Y307
K
L
A
E
A
F
K
Y
F
V
Q
G
M
G
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q62433
394
42990
S317
Q
G
M
G
Y
M
P
S
A
S
M
T
R
L
M
Rat
Rattus norvegicus
Q6JE36
394
42936
S317
Q
G
M
G
Y
M
P
S
A
S
M
T
R
L
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418430
402
44200
S317
Q
G
M
G
Y
M
P
S
A
S
M
T
R
L
M
Frog
Xenopus laevis
Q7ZWV3
396
43486
A318
Q
G
M
G
Y
M
P
A
A
S
M
T
R
L
M
Zebra Danio
Brachydanio rerio
Q5PR98
368
40449
G291
L
K
M
A
D
A
G
G
M
P
Q
L
T
Q
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O02485
325
35573
K249
T
T
H
K
S
M
N
K
K
K
T
T
L
L
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.5
99.2
94.1
N.A.
93.6
93.4
N.A.
N.A.
81.8
74.7
51.5
N.A.
N.A.
N.A.
25.1
N.A.
Protein Similarity:
100
69.5
99.4
95.9
N.A.
97.2
97.2
N.A.
N.A.
90.8
86.1
69
N.A.
N.A.
N.A.
44.1
N.A.
P-Site Identity:
100
0
100
0
N.A.
100
100
N.A.
N.A.
100
93.3
6.6
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
100
0
100
6.6
N.A.
100
100
N.A.
N.A.
100
100
6.6
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
10
10
10
0
10
60
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
10
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
0
% F
% Gly:
0
60
0
60
10
10
10
10
0
0
0
10
0
20
0
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
10
0
10
0
0
10
10
10
10
0
0
0
0
10
% K
% Leu:
10
10
0
0
0
0
0
0
0
10
0
10
10
70
0
% L
% Met:
10
0
70
0
0
70
0
0
10
0
60
0
10
0
60
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
60
10
0
10
0
0
10
0
10
% P
% Gln:
60
0
0
0
0
0
10
0
10
0
20
10
0
10
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
60
0
0
% R
% Ser:
0
0
0
10
10
0
0
50
0
60
0
0
0
0
0
% S
% Thr:
10
10
0
0
0
0
0
0
0
0
20
70
10
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
60
0
0
10
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _